KEGG   Miniopterus natalensis: 107539500
Entry
107539500         CDS       T05883                                 

Gene name
ADCY8
Definition
(RefSeq) adenylate cyclase type 8 isoform X1
  KO
K08048  adenylate cyclase 8 [EC:4.6.1.1]
Organism
mna  Miniopterus natalensis
Pathway
mna00230  Purine metabolism
mna01100  Metabolic pathways
mna01522  Endocrine resistance
mna04015  Rap1 signaling pathway
mna04020  Calcium signaling pathway
mna04022  cGMP-PKG signaling pathway
mna04024  cAMP signaling pathway
mna04062  Chemokine signaling pathway
mna04072  Phospholipase D signaling pathway
mna04114  Oocyte meiosis
mna04211  Longevity regulating pathway
mna04213  Longevity regulating pathway - multiple species
mna04261  Adrenergic signaling in cardiomyocytes
mna04270  Vascular smooth muscle contraction
mna04371  Apelin signaling pathway
mna04540  Gap junction
mna04611  Platelet activation
mna04713  Circadian entrainment
mna04714  Thermogenesis
mna04720  Long-term potentiation
mna04723  Retrograde endocannabinoid signaling
mna04724  Glutamatergic synapse
mna04725  Cholinergic synapse
mna04727  GABAergic synapse
mna04742  Taste transduction
mna04750  Inflammatory mediator regulation of TRP channels
mna04911  Insulin secretion
mna04912  GnRH signaling pathway
mna04913  Ovarian steroidogenesis
mna04914  Progesterone-mediated oocyte maturation
mna04915  Estrogen signaling pathway
mna04916  Melanogenesis
mna04918  Thyroid hormone synthesis
mna04921  Oxytocin signaling pathway
mna04923  Regulation of lipolysis in adipocytes
mna04925  Aldosterone synthesis and secretion
mna04926  Relaxin signaling pathway
mna04927  Cortisol synthesis and secretion
mna04928  Parathyroid hormone synthesis, secretion and action
mna04934  Cushing syndrome
mna04935  Growth hormone synthesis, secretion and action
mna04970  Salivary secretion
mna04971  Gastric acid secretion
mna04972  Pancreatic secretion
mna04976  Bile secretion
mna05032  Morphine addiction
mna05163  Human cytomegalovirus infection
mna05166  Human T-cell leukemia virus 1 infection
mna05200  Pathways in cancer
mna05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mna00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    107539500 (ADCY8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    107539500 (ADCY8)
   04371 Apelin signaling pathway
    107539500 (ADCY8)
   04020 Calcium signaling pathway
    107539500 (ADCY8)
   04072 Phospholipase D signaling pathway
    107539500 (ADCY8)
   04024 cAMP signaling pathway
    107539500 (ADCY8)
   04022 cGMP-PKG signaling pathway
    107539500 (ADCY8)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    107539500 (ADCY8)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    107539500 (ADCY8)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    107539500 (ADCY8)
   04062 Chemokine signaling pathway
    107539500 (ADCY8)
  09152 Endocrine system
   04911 Insulin secretion
    107539500 (ADCY8)
   04923 Regulation of lipolysis in adipocytes
    107539500 (ADCY8)
   04912 GnRH signaling pathway
    107539500 (ADCY8)
   04913 Ovarian steroidogenesis
    107539500 (ADCY8)
   04915 Estrogen signaling pathway
    107539500 (ADCY8)
   04914 Progesterone-mediated oocyte maturation
    107539500 (ADCY8)
   04921 Oxytocin signaling pathway
    107539500 (ADCY8)
   04926 Relaxin signaling pathway
    107539500 (ADCY8)
   04935 Growth hormone synthesis, secretion and action
    107539500 (ADCY8)
   04918 Thyroid hormone synthesis
    107539500 (ADCY8)
   04928 Parathyroid hormone synthesis, secretion and action
    107539500 (ADCY8)
   04916 Melanogenesis
    107539500 (ADCY8)
   04925 Aldosterone synthesis and secretion
    107539500 (ADCY8)
   04927 Cortisol synthesis and secretion
    107539500 (ADCY8)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    107539500 (ADCY8)
   04270 Vascular smooth muscle contraction
    107539500 (ADCY8)
  09154 Digestive system
   04970 Salivary secretion
    107539500 (ADCY8)
   04971 Gastric acid secretion
    107539500 (ADCY8)
   04972 Pancreatic secretion
    107539500 (ADCY8)
   04976 Bile secretion
    107539500 (ADCY8)
  09156 Nervous system
   04724 Glutamatergic synapse
    107539500 (ADCY8)
   04727 GABAergic synapse
    107539500 (ADCY8)
   04725 Cholinergic synapse
    107539500 (ADCY8)
   04720 Long-term potentiation
    107539500 (ADCY8)
   04723 Retrograde endocannabinoid signaling
    107539500 (ADCY8)
  09157 Sensory system
   04742 Taste transduction
    107539500 (ADCY8)
   04750 Inflammatory mediator regulation of TRP channels
    107539500 (ADCY8)
  09149 Aging
   04211 Longevity regulating pathway
    107539500 (ADCY8)
   04213 Longevity regulating pathway - multiple species
    107539500 (ADCY8)
  09159 Environmental adaptation
   04713 Circadian entrainment
    107539500 (ADCY8)
   04714 Thermogenesis
    107539500 (ADCY8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107539500 (ADCY8)
  09165 Substance dependence
   05032 Morphine addiction
    107539500 (ADCY8)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    107539500 (ADCY8)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    107539500 (ADCY8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    107539500 (ADCY8)
   05163 Human cytomegalovirus infection
    107539500 (ADCY8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    107539500 (ADCY8)
Enzymes [BR:mna01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     107539500 (ADCY8)
SSDB
Motif
Pfam: Guanylate_cyc DUF1053 AC_N TBK1_ULD
Other DBs
NCBI-GeneID: 107539500
NCBI-ProteinID: XP_016071485
LinkDB
Position
Unknown
AA seq 1067 aa
MNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQY
SGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQV
VLQVVIPRLAVISINQVVAQAVLFMCMNTAGISISYLSDRAQRQAFLETRRCVEARLRLE
TENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFT
NLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVE
MGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGG
IPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPEDIVKE
SVSSSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGP
EEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLL
SIAAIQSLLPSSRAMPMAIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINETYLA
RNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAM
VTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTKEASLLL
MAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFL
EKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGE
DRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNN
FELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGLSGRIQVPEETYLILKDQG
FAFDYRGEIYVKGISEQEGKLKTYFLLGRVQPNPLILPPRRLPGQYSLAAVVLGLVQSLN
RQRQKQLLTENNTTGIIKGHYNRRTLLTPSGSEPGTQAEGTDKSDLP
NT seq 3204 nt   +upstreamnt  +downstreamnt
atgaacgtgctggacgtgctgaccaaactcaccctcctggtgctccacctgagcctggcc
tcggcccccatggacccgctcaagggcatcctgctgggcttcttcacgggcatcgaggtg
gtgatctgcgcgctggtggtggtcaggaaggacaccacctcgcacacctacctgcagtac
agcggcgtggtcacctgggtggccatgaccacccagatcttggcagcaggccttggctac
gggctgctgggcgacggcatcggctatgtgctcttcaccctctttgccacctacagcatg
ctgccgctgccgctcacctgggccatcctggccggcctgggcacctcgctgctgcaggtg
gtcctccaagtggtgatcccccggctggcggtcatttccatcaaccaggtggtggcccag
gcggtgctgttcatgtgcatgaacacggcggggatctccatcagctacctgtcggaccgg
gcccagcgccaggccttcctggagacgcggcggtgcgtggaggcccggctgcgcctggag
acggaaaaccagagacaggagcggctggtgctgtctgtgctcccccggtttgtcgtcctg
gaaatgatcaacgacatgaccaacgtggaagacgagcacctgcagcaccagttccatcgg
atctacatccatcgctatgagaatgtcagtattctttttgcagatgttaaaggatttacc
aacctctccaccaccctgtctgctcaggagctggtcaggatgctcaacgagctctttgcc
agattcgatcgactggcccatgagcatcactgtcttcgcatcaaaatcttaggggactgc
tactattgtgtttctggacttcctgagccccgccaggaccatgcccactgctgcgttgaa
atgggcctcagcatgatcaaaaccatcaggtatgtgcggtcaaggacgaagcatgacgtt
gacatgcgaatcggaatccactcgggctcagtgctgtgtggtgtgttgggcctgcggaag
tggcagtttgacgtctggtcttgggacgtggacattgcgaacaaacttgaatctggagga
atccccgggaggattcacatttccaaagccacactcgactgcctcaacggtgactataac
gtggaagagggccacgggaaggagaggaatgagttcttgaggaagcataacatagagacc
tatttaattaagcagcccgaggagagtctgctgtccttgcccgaagacattgtcaaggag
tcagtgagctcctcagacaggaggaacagtggggcgacattcacagaagggtcctggagc
cccgagctgcccttcgacaacatagtggggaaacagaacactctggctgccctaacaaga
aattcaataaatctacttccaaaccatctcgcacaagctttgcatgtccagtcggggcct
gaggaaattaacaagcgaatagaacataccatcgacttgcggagtggcgataaattgaga
agagagcatatcaagccattctcactgatgtttaaagactccagcctggagcacaagtat
tctcagatgagggacgaagtgttcaagtccaacctggtctgcgcctttatcgtcctcctg
tccatcgcggccatacaaagcctgcttccttcttcaagggcgatgcccatggccatccag
ttttccatcctgatcatgctgcactcggcactggtcctcatcaccacggcggaggattac
aagtgtctgcccctggtcctccggaaaacttgctgttggatcaacgagacctatttggcc
cggaacgtcatcatcttcgcgtccatcctgattaatttcctgggcgccatcctgaatatc
ctgtggtgtgattttgacaagtcgatacccttgaagaacctgactttcaattcctcagct
gtgtttacagatatctgctcctacccagagtacttcgtcttcacgggtgtgttggccatg
gtgacctgtgcggttttcctccgacttaactctgtcctgaagctggctgtgctgctcatt
atgatcgccatctatgccctgctgaccgagaccatctacgcaggtctctttctgcgctat
gacaacctgaaccacagtggagaagatttcctggggaccaaggaggcgtcgctgctgctg
atggccatgttcctccttgctgtgttctaccatggacagcagctggagtacacagcccgc
ctggacttcctctggcgagtgcaggccaaagaggaaatcaacgagatgaaggagctgagg
gagcacaacgagaacatgctgcggaacatcctcccgagccacgtggcccgccacttcctg
gagaaggaccgcgacaacgaggagctgtattctcagtcctacgatgccgtcggggtgatg
ttcgcctccatcccggggttcgccgacttctactctcagaccgagatgaacaaccaagga
gtggagtgcctgcgcctgctgaacgagatcatcgctgacttcgatgagctgctcggtgaa
gaccggtttcaagacattgaaaagatcaagaccatcggcagcacctacatggctgtctca
ggcctgtcacctgaaaagcagcaatgtgaagataagtggggacacctgtgtgccctggcc
gacttctctctcgccctgactgaaagcatacaggaaatcaacaagcattcgttcaacaat
tttgaactccggattggcatcagccacggctcggtggtagccggcgtcattggcgctaag
aaaccacagtacgacatctggggcaaaaccgtgaacctggccagccggatggacagcacc
gggctcagcggccggatccaggtcccggaggagacctatctcatcctgaaggaccagggc
ttcgccttcgactatcgcggggagatctacgtgaagggcatcagtgagcaggaggggaag
ctcaaaacgtactttctcctggggagagtgcagcccaacccgctgatcctgcccccgcgg
aggctgccgggccagtactccctggccgccgtggtcctgggccttgtccagtccctcaac
aggcaacggcagaagcagctgctcaccgagaacaacaccacgggcatcatcaagggccac
tacaaccggcggactttgttgacacccagcgggtcagagcctgggacccaagccgagggc
accgacaagtccgatttgccataa

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