Mus pahari (shrew mouse): 110331339
Help
Entry
110331339 CDS
T05929
Gene name
Erbb2
Definition
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
mpah
Mus pahari (shrew mouse)
Pathway
mpah01521
EGFR tyrosine kinase inhibitor resistance
mpah01522
Endocrine resistance
mpah01524
Platinum drug resistance
mpah04010
MAPK signaling pathway
mpah04012
ErbB signaling pathway
mpah04020
Calcium signaling pathway
mpah04066
HIF-1 signaling pathway
mpah04151
PI3K-Akt signaling pathway
mpah04510
Focal adhesion
mpah04520
Adherens junction
mpah04530
Tight junction
mpah05200
Pathways in cancer
mpah05205
Proteoglycans in cancer
mpah05206
MicroRNAs in cancer
mpah05212
Pancreatic cancer
mpah05213
Endometrial cancer
mpah05215
Prostate cancer
mpah05219
Bladder cancer
mpah05223
Non-small cell lung cancer
mpah05224
Breast cancer
mpah05226
Gastric cancer
mpah05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mpah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110331339 (Erbb2)
04012 ErbB signaling pathway
110331339 (Erbb2)
04066 HIF-1 signaling pathway
110331339 (Erbb2)
04020 Calcium signaling pathway
110331339 (Erbb2)
04151 PI3K-Akt signaling pathway
110331339 (Erbb2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
110331339 (Erbb2)
04520 Adherens junction
110331339 (Erbb2)
04530 Tight junction
110331339 (Erbb2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110331339 (Erbb2)
05206 MicroRNAs in cancer
110331339 (Erbb2)
05205 Proteoglycans in cancer
110331339 (Erbb2)
05230 Central carbon metabolism in cancer
110331339 (Erbb2)
09162 Cancer: specific types
05212 Pancreatic cancer
110331339 (Erbb2)
05226 Gastric cancer
110331339 (Erbb2)
05219 Bladder cancer
110331339 (Erbb2)
05215 Prostate cancer
110331339 (Erbb2)
05213 Endometrial cancer
110331339 (Erbb2)
05224 Breast cancer
110331339 (Erbb2)
05223 Non-small cell lung cancer
110331339 (Erbb2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110331339 (Erbb2)
01524 Platinum drug resistance
110331339 (Erbb2)
01522 Endocrine resistance
110331339 (Erbb2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mpah01001
]
110331339 (Erbb2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mpah04147
]
110331339 (Erbb2)
04090 CD molecules [BR:
mpah04090
]
110331339 (Erbb2)
Enzymes [BR:
mpah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
110331339 (Erbb2)
Protein kinases [BR:
mpah01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
110331339 (Erbb2)
Exosome [BR:
mpah04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
110331339 (Erbb2)
CD molecules [BR:
mpah04090
]
Proteins
110331339 (Erbb2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
APH
Kinase-like
DUF5849
EphA2_TM
Motif
Other DBs
NCBI-GeneID:
110331339
NCBI-ProteinID:
XP_021067486
Ensembl:
MGP_PahariEiJ_G0018213
LinkDB
All DBs
Position
14
AA seq
1255 aa
AA seq
DB search
MELAAWCRWGFLLALLPPGAASTHVCTGTDMKLRFPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPANASLSFLQDIQEVQGYMLIAHNRVRHIPLQRLRIVRGTQLFEDKYALAVLDNR
DPLDNVTAAPGRTPEGLRELRLRSLTEILKGGVLIRGNPQLCYQDMVLWKDVLRKNNQLA
PVDVDTNRSRACPPCAPTCKDNHCWGESPEDCQILTGTICTSGCARCKGRLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALITYNTDTFESMLNPEGRYTFGASCVTTCP
YNYLSTEVGSCTLVCPPNNQEVTAEDGTQRCEKCSKPCAEVCYGLGMEHLRGARAITSDN
IQEFAGCKKIFGSLAFLPESFDGNPSSGIAPLKPEHLQVFETLEEITGYLYISAWPESLQ
DLSVFQNLRVIRGRILHDGAYSLTLQGLGIHSLGLRSLRELGSGLALIHRNTHLCFVHTV
PWDQLFRNPHQALLHSGNRPEEACGLEGLVCNSLCAHGYCWGPGPTQCVNCSQFLRGQEC
VEECRVWKGLPREYVSGKHCLPCHPECQPQNSSETCFGSEADQCAACAHYKDSSFCVARC
PSGVKPDLSYMPIWKYPDEEGICQPCPINCTHSCVDLDERGCPAEQRASPVTFIIATVVG
VLLFLIIVVVIGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAVPNQAQMRILKETEL
RKLKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPVCTIDVYMIMVKCWM
IDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPSSPMDSTFYRSLLEDDDMGELVDA
EEYLVPQQGFFSPDPAPGTGSTAHRRHRSSSARSGGGELTLGLEPSEEEPPRSPLAPSEG
AGSDVFDGDLAVGVTKGLQSLSPHDLSPLQRYSEDPTLPLPPETDGYVAPLACSPQPEYV
NQPEVRPQPPMTPEGPPPPVRPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLAPR
EGTASQPRPSPAFSPAFDNLYYWDQNSSEQGPPPSTFEGTPTAENPEYLGLDVPV
NT seq
3768 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgttgggggttcctcctcgccctcctgccccccggagcc
gcgagtacccatgtgtgtaccggcacagacatgaagttgcggttccctgccagtcctgag
acccacctggacatgctccgccacctctaccagggctgtcaggtggtgcagggcaacttg
gaacttacgtacctgcccgccaatgccagcctctcgttcctgcaggacatccaggaagtc
cagggatacatgctcatcgctcacaaccgagtgaggcacatcccactgcagaggctgcgc
atcgtgagagggactcagctcttcgaggacaagtacgccctagctgtgctagacaaccga
gatcctttggacaacgtcaccgccgccccaggcagaaccccagaagggctgcgggagctg
cggctgcgaagtctcacagagatcctgaagggaggagttttgatccgtgggaacccgcag
ctctgctaccaggacatggttttgtggaaggatgtcctccgcaagaataaccagctggct
cctgtcgacgtagacaccaatcgttcccgggcctgtccaccttgcgccccaacttgcaaa
gacaatcactgttggggtgagagccctgaagactgtcagatcttgactggcaccatctgt
accagtggctgtgcccggtgcaagggccggctgcccactgactgttgccacgagcagtgt
gctgcaggctgcacgggccccaagcattctgactgcctggcctgcctccacttcaatcat
agtggtatctgtgagctgcactgcccggccctcatcacctacaacacagacaccttcgag
tccatgctcaaccctgagggccgctacacctttggtgccagctgtgtgaccacctgcccc
tacaactacctctccacggaagtgggatcctgcactctggtctgtcccccgaacaaccaa
gaggtcacagctgaggacgggacacagcggtgtgagaaatgcagcaagccctgtgctgaa
gtgtgctatggtttgggcatggagcacctccgaggggccagggccatcaccagtgacaat
atccaggagtttgctggctgcaagaagatctttgggagcctggcatttttgccggagagc
tttgatgggaacccctcctctggcattgccccactgaagccggagcatctccaagtgttc
gaaaccctggaggagatcacaggttacctatacatttcagcgtggccagagagcctccaa
gacctcagtgtcttccagaaccttcgggtcattcggggacggattctccatgatggtgct
tactcactgacgctgcaaggcctggggattcactcgctggggctgcgttcactgcgggag
ctgggcagtggattggctctcattcaccgcaacacccatctttgctttgtacacactgta
ccttgggaccagctcttccggaaccctcaccaggccctgctccacagcgggaaccggccg
gaagaggcgtgtggtcttgagggcttggtctgtaactcactgtgtgcccatgggtactgc
tgggggccagggcccacccagtgtgtcaactgcagtcagttcctccggggccaggagtgt
gtggaggagtgccgagtatggaaggggctccccagggagtatgtgagtggcaagcactgt
ctgccatgccaccccgagtgtcagcctcagaacagttccgagacctgctttggatcggag
gctgaccagtgtgcagcttgtgcccactacaaggactcatccttctgtgtggctcgctgc
cccagtggtgtgaaaccagacctctcctacatgcccatctggaagtacccggatgaggag
ggcatatgtcagccatgccccatcaactgcacccactcctgtgtggacctggacgaacga
ggctgcccggcagagcagagagccagcccggtgacattcatcattgcaactgtggtgggc
gtcctgttgttcctgatcatcgtggtagtcattggaatcctaatcaagcgaaggcgacag
aagatccggaagtataccatgcgtaggctgctgcaggagactgagctggtggagccgctg
acgcccagcggagcggtgcccaaccaggctcagatgcggatcctaaaggagacggagcta
aggaagctgaaggtgcttggatcaggagccttcggcactgtctacaagggcatctggatc
ccagatggggagaacgtgaaaatccccgtggccatcaaggtgttgagggaaaacacatct
cctaaagctaacaaagaaatcctagatgaagcctatgtcatggctggtgtgggttctccg
tatgtgtcccgtctcctgggcatctgcctgacatccacagtgcagctggtgacacagctt
atgccctatggctgccttctggaccatgtccgagaacatcgaggtcgcctaggctcccag
gacctgctcaactggtgtgttcagattgccaaggggatgagctacctggaggacgttcgg
cttgttcacagggacctagctgcccggaacgtgctagtcaagagtcccaaccacgtcaag
attactgacttcgggctggcccggctgctcgacattgatgagactgaataccatgcagat
gggggcaaggtgcccatcaagtggatggcattggaatctattctcagacgccggttcacc
catcagagtgatgtgtggagctatggtgtgactgtgtgggagctgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccccgatttgctggagaagggagaacgc
ctacctcagcctccagtctgcaccatcgatgtctacatgatcatggtcaaatgttggatg
attgattccgaatgtcgcccgagattccgggagttagtatcagagttctcccgtatggcg
agggacccccagcgctttgtggtcatccagaacgaggacttgggcccttccagccccatg
gacagcactttctaccgttcactgctggaggatgatgacatgggggagctggtcgatgct
gaagagtacctggtaccccagcagggattcttctccccagaccctgccccaggtaccggg
agcacagcccaccgcagacaccgcagctcgtcggccaggagtggcggtggtgagctgacg
ctgggcctggagccctcggaagaagagccccccagatctccactggctccctccgaaggg
gctggctccgatgtgtttgatggtgacctggcagtgggggtaaccaaaggactgcagagc
ctctctccacatgacctcagccctctacagcggtacagtgaggatcccacattacctctg
ccccccgagactgatggctacgttgctcccctggcctgcagcccccagcccgagtatgtg
aaccagccagaggttcggcctcagcctcccatgaccccagagggtcctcctcctcctgtc
cgacctgccggtgctactctagaaagacccaagactctctctcctgggaagaatggggtt
gtcaaagacgtttttgcctttgggggtgctgtggagaaccctgaatacttagcacccaga
gaaggcactgcctctcagccccgcccttctcctgccttcagcccagcctttgacaatctc
tattactgggaccagaactcatcggagcaggggcctccaccaagtacctttgaagggacc
cccactgcagagaaccccgagtacctaggcctggatgtgccagtatga
DBGET
integrated database retrieval system
