KEGG   Mus pahari (shrew mouse): 110332765
Entry
110332765         CDS       T05929                                 

Gene name
Stat3
Definition
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
mpah  Mus pahari (shrew mouse)
Pathway
mpah01521  EGFR tyrosine kinase inhibitor resistance
mpah04062  Chemokine signaling pathway
mpah04066  HIF-1 signaling pathway
mpah04068  FoxO signaling pathway
mpah04217  Necroptosis
mpah04550  Signaling pathways regulating pluripotency of stem cells
mpah04630  JAK-STAT signaling pathway
mpah04659  Th17 cell differentiation
mpah04917  Prolactin signaling pathway
mpah04920  Adipocytokine signaling pathway
mpah04931  Insulin resistance
mpah04933  AGE-RAGE signaling pathway in diabetic complications
mpah04935  Growth hormone synthesis, secretion and action
mpah05145  Toxoplasmosis
mpah05160  Hepatitis C
mpah05161  Hepatitis B
mpah05162  Measles
mpah05163  Human cytomegalovirus infection
mpah05167  Kaposi sarcoma-associated herpesvirus infection
mpah05169  Epstein-Barr virus infection
mpah05200  Pathways in cancer
mpah05203  Viral carcinogenesis
mpah05205  Proteoglycans in cancer
mpah05206  MicroRNAs in cancer
mpah05212  Pancreatic cancer
mpah05221  Acute myeloid leukemia
mpah05223  Non-small cell lung cancer
mpah05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mpah05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:mpah00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    110332765 (Stat3)
   04066 HIF-1 signaling pathway
    110332765 (Stat3)
   04068 FoxO signaling pathway
    110332765 (Stat3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    110332765 (Stat3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    110332765 (Stat3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    110332765 (Stat3)
   04062 Chemokine signaling pathway
    110332765 (Stat3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    110332765 (Stat3)
   04917 Prolactin signaling pathway
    110332765 (Stat3)
   04935 Growth hormone synthesis, secretion and action
    110332765 (Stat3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110332765 (Stat3)
   05206 MicroRNAs in cancer
    110332765 (Stat3)
   05205 Proteoglycans in cancer
    110332765 (Stat3)
   05203 Viral carcinogenesis
    110332765 (Stat3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    110332765 (Stat3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    110332765 (Stat3)
   05221 Acute myeloid leukemia
    110332765 (Stat3)
   05223 Non-small cell lung cancer
    110332765 (Stat3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    110332765 (Stat3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    110332765 (Stat3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    110332765 (Stat3)
  09172 Infectious disease: viral
   05162 Measles
    110332765 (Stat3)
   05161 Hepatitis B
    110332765 (Stat3)
   05160 Hepatitis C
    110332765 (Stat3)
   05163 Human cytomegalovirus infection
    110332765 (Stat3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    110332765 (Stat3)
   05169 Epstein-Barr virus infection
    110332765 (Stat3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    110332765 (Stat3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    110332765 (Stat3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mpah03000]
    110332765 (Stat3)
Transcription factors [BR:mpah03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    110332765 (Stat3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135 DUF4795 Syntaxin-6_N AP1AR Fib_alpha
Other DBs
NCBI-GeneID: 110332765
NCBI-ProteinID: XP_021069767
Ensembl: MGP_PahariEiJ_G0018320
LinkDB
Position
14
AA seq 770 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVDLFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMDLTSECATSPM
NT seq 2313 nt   +upstreamnt  +downstreamnt
atggctcagtggaaccagctgcagcagctggacacacgctacctggagcagctgcaccag
ctgtacagcgacagcttccccatggagttgcggcagttcctggcaccttggattgagagt
caagactgggcatatgcagccagcaaagagtcacatgccacgttggtgtttcataatctc
ctgggtgaaattgaccagcaatatagccgattcctgcaagagtccaatgtcctctatcag
cacaaccttcggagaatcaagcagtttctgcagagcaggtatctcgagaagccaatggaa
attgcccgaatcgtggcccgatgcctgtgggaagagtctcgcctcctccagacagcggcc
acggcagcccagcaagggggtcaggccaaccacccaacagctgctgtagtgacagagaag
cagcagatgttggagcagcatcttcaggatgtccggaagcgtgtgcaggatctagaacag
aaaatgaaagtggtagagaatctccaggacgactttgatttcaactataaaaccctcaag
agtcaaggagacatgcaggatctgaatggaaacaaccagtctgtgacccgacagaagatg
cagcagctggaacagatgctcacagccctggaccagatgcggagaagcatcgtgagtgag
ctggcagggctcttgtcagcaatggagtatgtgcagaagacactgaccgatgaagagctg
gccgactggaagaggcggcagcagatagcgtgcatcggaggccctcccaacatctgcctg
gaccgtctggaaaactggataacttcattagcagaatctcaacttcagacccgccaacaa
attaagaaactggaggagctgcagcagaaagtgtcctacaagggcgacccgattgtgcag
caccggcccatgctggaggagaggattgtggatctgttcagaaacttaatgaagagtgcc
ttcgtggtggagcggcagccctgcatgcccatgcacccggaccggcccttagtcatcaag
actggtgtccagtttaccaccaaagtcaggttgctggtcaaatttcctgagttgaattat
cagcttaaaattaaagtgtgcattgataaagactctggggatgttgctgccctcaggggg
tcccggaaatttaacattctgggcacgaacacaaaagtgatgaacatggaggagtctaac
aacggcagcctgtctgcagagttcaagcacctgaccctgagggagcagagatgtgggaat
ggaggccgtgccaattgtgatgcctccttgattgtgactgaggagctgcacctgatcacc
tttgagactgaggtgtaccaccaaggcctcaagatcgacctagagacccactccttgcca
gttgtggtgatctccaacatctgtcagatgccaaatgcttgggcatcaatcctgtggtat
aacatgctgaccaataaccccaagaacgtgaacttcttcactaagccgccgattggaacc
tgggaccaagtggcggaggtgctcagctggcagttctcgtccaccacaaagcgggggctg
agcatcgagcagctgaccacactggccgagaagctcttagggcctggtgtgaactactcg
gggtgtcagatcacatgggctaaattctgcaaagaaaacatggctggcaagggcttctcc
ttctgggtctggctagacaatatcatcgaccttgtgaaaaagtatatcttggccctttgg
aatgaagggtacatcatgggtttcatcagcaaggagcgggagcgggccatcctaagcaca
aagcccccgggcaccttcctgctgcggttcagcgagagcagcaaagaaggaggggtcact
ttcacttgggtggaaaaggacatcagtggcaagacccagatccagtctgtagagccatac
accaagcagcagctgaacaacatgtcatttgctgaaatcatcatgggctataagatcatg
gatgcgaccaacatcctggtgtctccacttgtctacctctaccctgacattcccaaggag
gaggcattcggaaagtattgtaggcccgagagccaggagcaccccgaagctgacccaggt
agtgctgccccttacctgaagaccaagttcatctgtgtgacaccaacgacctgcagcaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataac
ggtgaaggtgctgagccctcagcaggagggcagtttgagtcgctcacgtttgacatggat
ctgacctcggagtgtgctacctcccccatgtga

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