Mycolicibacterium smegmatis MC2 155: MSMEI_2327
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Entry
MSMEI_2327 CDS
T02191
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
msg
Mycolicibacterium smegmatis MC2 155
Pathway
msg00290
Valine, leucine and isoleucine biosynthesis
msg00660
C5-Branched dibasic acid metabolism
msg01100
Metabolic pathways
msg01110
Biosynthesis of secondary metabolites
msg01210
2-Oxocarboxylic acid metabolism
msg01230
Biosynthesis of amino acids
Module
msg_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
msg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MSMEI_2327 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MSMEI_2327 (leuC)
Enzymes [BR:
msg01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MSMEI_2327 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MSMEI_2327 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Latexin_N
Motif
Other DBs
NCBI-ProteinID:
AFP38795
UniProt:
I7FB77
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Position
2470807..2472261
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AA seq
484 aa
AA seq
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MDQPTQTSVKPRTLAEKVWDDHVVARGEGEGTAKEPDLIYIDLHLVHEVTSPQAFDGLRL
AGRPVRRPDLTIATEDHNVPTIDIDKPIADPVSRTQVETLRRNCEEFGIRLHPMGDAEQG
IVHIIGPQLGLTQPGMTVVCGDSHTSTHGAFGAIAMGIGTSEVEHVMATQTLSLKPFKTM
AVNVDGELPPGVSAKDIILAVIAKIGTGGGQGHVIEYRGSAIRSLSMEGRMTICNMSIEA
GARAGMVAPDETTFEFLKGRPHAPKGADWDAAVAAWSRLRTDEGAEFDTEVYIDASTLSP
FVTWGTNPGQGVPLSEAVPDPELIVDEGARQAAEKALAYMDLRPGTPMRDIAVDTVFVGS
CTNGRIEDLRVVADVLRGRKVADGVRMLIVPGSMRVRAQAESEGLDQIFTAAGAQWRQAG
CSMCLGMNPDQLSPGERCASTSNRNFEGRQGKGGRTHLVSPAVAAATAVRGKLASPADLP
AAAR
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggatcaaccgacgcagacatccgtgaaaccgcgcaccctggccgaaaaggtctgggac
gaccacgtcgtggcgcgtggcgagggagagggcaccgccaaagagcccgatctgatctac
atcgacctccatctcgtccacgaggtcaccagcccgcaggccttcgacgggctgcggctg
gccggacgtcccgtgcggcggcccgatctgacgatcgccaccgaggaccacaacgtgccg
accatcgacatcgacaagccgatcgccgacccggtttcgcgcacccaggtcgagacattg
cggcgcaactgcgaggaattcggcatccgcctgcatcccatgggcgacgccgaacagggc
atcgttcacatcatcggcccgcagctgggcctcacccagcccgggatgaccgtggtgtgc
ggtgactcgcacacgtcgacccacggcgccttcggtgccatcgcgatgggcatcggcacc
tccgaggtcgagcacgtgatggccacgcagacgctgtcgctcaagcccttcaagaccatg
gcggtcaacgtcgacggcgaactgccgcccggcgtgagcgccaaggacatcatcctggcg
gtgatcgccaagatcggcaccggcggtgggcagggacacgtcatcgagtaccgcggcagc
gccatccgctcgctgtccatggagggccggatgacgatctgcaacatgagcatcgaggcc
ggcgcccgcgcgggcatggtcgcgcccgacgagaccacgttcgagttcctcaagggtcgt
ccgcacgcgcccaagggcgccgactgggacgccgccgtcgccgcgtggagccggttgcgc
accgacgagggcgccgaattcgacaccgaggtctacatcgacgcctccacgctgagcccg
ttcgtgacctggggcaccaaccccggccagggcgttccgctgtcggaggccgtgcccgac
cccgagctgatcgtcgacgagggcgcccgtcaggccgcggaaaaggctttggcctacatg
gaccttcgcccgggtaccccgatgcgcgacatcgccgtggacacggtgttcgtgggctcg
tgcaccaacggccggatcgaggatctgcgcgtggtggccgacgtgctgcgcggccggaag
gttgccgacggcgtgcggatgctcatcgtcccgggttcgatgcgggtgcgcgcacaggcc
gaatcggaaggcctcgaccagatattcaccgcagccggggcccaatggcgccaggccggg
tgctcgatgtgcctcgggatgaaccccgatcagctctccccgggggagcgctgcgcgtcg
acgtccaaccgcaacttcgagggtcgccagggcaagggcggccgcacccacctggtgtcg
cctgctgtcgccgcagccaccgccgtgcgcggaaagctcgcgtcccctgcagatctaccc
gccgcggcccgctag
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