Mycobacterium tuberculosis CCDC5180: CCDC5180_2273
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Entry
CCDC5180_2273 CDS
T01992
Name
(GenBank) pyruvate dehydrogenase E1 component alpha subunit pdhA
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
mtl
Mycobacterium tuberculosis CCDC5180
Pathway
mtl00280
Valine, leucine and isoleucine degradation
mtl00640
Propanoate metabolism
mtl00785
Lipoic acid metabolism
mtl01100
Metabolic pathways
mtl01110
Biosynthesis of secondary metabolites
mtl01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mtl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
CCDC5180_2273
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
CCDC5180_2273
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CCDC5180_2273
Enzymes [BR:
mtl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
CCDC5180_2273
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
MCD
Motif
Other DBs
NCBI-ProteinID:
AEJ51110
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Position
complement(2799200..2800273)
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AA seq
357 aa
AA seq
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MLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGEL
ALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQF
TTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFT
TPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARA
RAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRL
EEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD
NT seq
1074 nt
NT seq
+upstream
nt +downstream
nt
atgttgatgtctgtcgatcttgagccggtgcaactcgtcggcccggacggtacgccgacg
gccgaacgccgctaccaccgtgaccttcctgaggaaacgctgcgttggctctacgagatg
atggtggtcacccgcgagctggataccgaattcgtcaatctgcagcgccagggggagctg
gcgttgtacacgccctgtcgcgggcaggaagccgcgcaggtgggtgcggcggcttgccta
cgcaaaaccgactggttgttcccccaataccgagaattgggcgtctacctagtgcgtggc
atcccgcctggacatgttggggtcgcgtggcgtggaacctggcacggcgggctgcaattc
accacgaagtgctgtgcaccgatgtcggttcccatcggcacccagaccttgcacgcggtg
ggcgcggcgatggccgcgcaacgcctggacgaggactccgtgacggtggcctttctgggc
gacggcgccaccagcgagggcgacgtacatgaggcgctcaatttcgcggcggtgttcacc
acaccgtgcgtgttctacgtgcagaacaaccagtgggcaatctcgatgccggtatccagg
cagaccgccgcaccatctatcgcgcacaaggcgattggctacgggatgccaggcatccgg
gtggacggcaacgacgtgctggcatgctatgcggtgatggccgaagctgccgctcgggct
cgggccggcgacggtccaacgctgatcgaggcggtcacttaccgtcttggtccgcacacc
accgccgatgatccaacccggtaccgcagccaggaggaggtggaccgctgggcgacgctg
gacccgattccgcgctatcgcacttacttacaagatcagggcctgtggtcgcaacgcctc
gaggaacaggtgacggctcgggcaaaacacgtgcggtccgagctacgcgacgcggtcttt
gatgcgcctgacttcgacgtcgatgaggtgttcaccacggtgtacgccgaaatcacaccc
gggttgcaggcgcagcgcgaacagctgcgtgccgaactggcgcggactgactga
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