Mycobacterium tuberculosis Erdman = ATCC 35801: ERDMAN_0859
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Entry
ERDMAN_0859 CDS
T02526
Symbol
purB
Name
(GenBank) adenylosuccinate lyase
KO
K01756
adenylosuccinate lyase [EC:
4.3.2.2
]
Organism
mtn
Mycobacterium tuberculosis Erdman = ATCC 35801
Pathway
mtn00230
Purine metabolism
mtn00250
Alanine, aspartate and glutamate metabolism
mtn01100
Metabolic pathways
mtn01110
Biosynthesis of secondary metabolites
mtn01232
Nucleotide metabolism
mtn01240
Biosynthesis of cofactors
Module
mtn_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
mtn_M00049
Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
Brite
KEGG Orthology (KO) [BR:
mtn00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
ERDMAN_0859 (purB)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
ERDMAN_0859 (purB)
Enzymes [BR:
mtn01000
]
4. Lyases
4.3 Carbon-nitrogen lyases
4.3.2 Amidine-lyases
4.3.2.2 adenylosuccinate lyase
ERDMAN_0859 (purB)
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Gene cluster
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Motif
Pfam:
Lyase_1
ADSL_C
Motif
Other DBs
NCBI-ProteinID:
BAL64670
UniProt:
A0A0H3L6I7
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Position
869908..871326
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AA seq
472 aa
AA seq
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MSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD
DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF
AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR
YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV
SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR
GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE
LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR
LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL
NT seq
1419 nt
NT seq
+upstream
nt +downstream
nt
gtgagcattcccaacgtgctggccacccgatacgccagcgccgagatggtcgcgatctgg
tcgccggaggccaaggtggtctcggagcggcggttatggctggccgtattgcgggcacag
gcagagctgggggtagcggttgccgattcggtgctcgccgactacgaacgtgtggtcgac
gatgtggacttggcctcgatctcagcccgggagcgggtgctgcgccacgatgtcaaggcc
cgcatcgaggaattcaacgcattggccggtcatgagcacgtgcacaaggggatgaccagc
cgcgacctgaccgagaacgtggagcaactgcagattcggcggtcgctggaagtgattttc
gcccatggggtggcggcggtggcgcggctggccgagcgggcggtgagctaccgtgacctg
atcatggccgggcgcagccacaacgtggccgctcaggccaccaccttgggcaagcggttc
gcctcggcggcccaagagatgatgatcgcgttgaggcggttgagggagttgatcgaccgc
taccccctgcgtggcatcaagggcccgatgggcaccggtcaggacatgctcgatctgctg
ggcggtgaccgtgcggcgctggccgatctcgagcggcgcgtcgccgacttcttgggcttt
gcaactgttttcaacagcgtggggcaggtgtatccgcgttcattggaccacgacgtggtt
tcggctctggtgcagctcggcgcggggccgtcatcactggcacacacgattcgattgatg
gccggccacgagctcgccaccgagggtttcgcgccgggtcaggtcggttcgtcggcgatg
ccgcacaagatgaacacccgcagctgcgaacgggtcaacgggctgcaggttgtgctacgc
ggctatgcatccatggtggccgagttagccggtgcacagtggaacgagggtgatgtgttt
tgctccgtggtgcgccgggttgcgttgccggacagcttctttgccgtcgacgggcagatc
gagacgtttttgacggtgctggacgagttcggcgcctacccggcggtgatcggccgcgag
ttggatcgttatctgccgttcctggccaccactaaggtgctaatggcggccgtgcgcgcg
gggatgggtcgcgagtccgcgcaccggttgatctccgagcacgcggtggcgacggcgctg
gccatgcgagaacacggcgcggagcccgacctgctggaccggttggccgccgatccgcgg
ctgacgctgggacgagacgctttggaggccgcgctggccgacaagaaggcatttgccggt
gccgcgggtgaccaggtcgatgatgtggtcgcgatggtggacgcgctggtgagccgttac
ccggacgcggctaaatacacgccgggtgcaattctttag
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