KEGG   Meriones unguiculatus (Mongolian gerbil): 110549049
Entry
110549049         CDS       T05884                                 

Gene name
Tbk1
Definition
(RefSeq) serine/threonine-protein kinase TBK1
  KO
K05410  TANK-binding kinase 1 [EC:2.7.11.10]
Organism
mun  Meriones unguiculatus (Mongolian gerbil)
Pathway
mun04014  Ras signaling pathway
mun04137  Mitophagy - animal
mun04140  Autophagy - animal
mun04620  Toll-like receptor signaling pathway
mun04621  NOD-like receptor signaling pathway
mun04622  RIG-I-like receptor signaling pathway
mun04623  Cytosolic DNA-sensing pathway
mun04657  IL-17 signaling pathway
mun05014  Amyotrophic lateral sclerosis
mun05022  Pathways of neurodegeneration - multiple diseases
mun05135  Yersinia infection
mun05160  Hepatitis C
mun05161  Hepatitis B
mun05162  Measles
mun05163  Human cytomegalovirus infection
mun05164  Influenza A
mun05165  Human papillomavirus infection
mun05167  Kaposi sarcoma-associated herpesvirus infection
mun05168  Herpes simplex virus 1 infection
mun05169  Epstein-Barr virus infection
mun05170  Human immunodeficiency virus 1 infection
mun05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:mun00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    110549049 (Tbk1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    110549049 (Tbk1)
   04137 Mitophagy - animal
    110549049 (Tbk1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    110549049 (Tbk1)
   04621 NOD-like receptor signaling pathway
    110549049 (Tbk1)
   04622 RIG-I-like receptor signaling pathway
    110549049 (Tbk1)
   04623 Cytosolic DNA-sensing pathway
    110549049 (Tbk1)
   04657 IL-17 signaling pathway
    110549049 (Tbk1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    110549049 (Tbk1)
   05022 Pathways of neurodegeneration - multiple diseases
    110549049 (Tbk1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    110549049 (Tbk1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    110549049 (Tbk1)
   05161 Hepatitis B
    110549049 (Tbk1)
   05160 Hepatitis C
    110549049 (Tbk1)
   05171 Coronavirus disease - COVID-19
    110549049 (Tbk1)
   05164 Influenza A
    110549049 (Tbk1)
   05162 Measles
    110549049 (Tbk1)
   05168 Herpes simplex virus 1 infection
    110549049 (Tbk1)
   05163 Human cytomegalovirus infection
    110549049 (Tbk1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    110549049 (Tbk1)
   05169 Epstein-Barr virus infection
    110549049 (Tbk1)
   05165 Human papillomavirus infection
    110549049 (Tbk1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mun01001]
    110549049 (Tbk1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mun04131]
    110549049 (Tbk1)
Enzymes [BR:mun01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     110549049 (Tbk1)
Protein kinases [BR:mun01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   110549049 (Tbk1)
Membrane trafficking [BR:mun04131]
 Autophagy
  Xenophagy
   Other xenophagy associated proteins
    110549049 (Tbk1)
SSDB
Motif
Pfam: TBK1_CCD1 Pkinase TBK1_ULD PK_Tyr_Ser-Thr Pkinase_fungal DUF713 Kinase-like CEP63 ubiquitin
Other DBs
NCBI-GeneID: 110549049
NCBI-ProteinID: XP_021493529
LinkDB
Position
Unknown
AA seq 732 aa
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLYAVKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSADMPVSCSLSQGLQALLTPVLANILEADQEKCWGFDQFFA
ETSDVLHRMIIHVFSLQQMTAHKIYIHSYNTAAVFHELVYKQTKISSSNQELIYEGRRLV
LELGRLAQHFPKTTEENPIFVISREPLPTLSILGLKYEKISLPKVHPRYDLDGDASMAKA
VTGVVCYACRIASTLLLYQELMRKGVRWVIELVKDDFNETVHKKTEVVITLEFCIRNIEK
TVKVYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIESSLQDIKSRLSPGGLLADTWA
HQEGTHPRDRNVEKLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKA
MSHFTDECVRKYEVFLAKSDEWLRKMFHLRKQLSSLTNQCFDIEEEVSKYQDYTNELQET
LPQKMLAASSGLKHSMAPVYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSL
TMDGGLRNVDCL
NT seq 2199 nt   +upstreamnt  +downstreamnt
atgcagagcacttctaaccatctgtggcttttgtctgatatcttaggccagggggccact
gcaaatgtcttccgaggaagacataagaaaactggcgacttatatgctgtcaaagtattt
aataacatcagcttccttcgccccgtggatgttcaaatgagagaatttgaagtgttaaaa
aaactcaatcacaaaaacattgtcaaactttttgctattgaggaggagacaacaacaaga
cataaagtacttattatggaattttgtccctgtgggagtttatacacagttctggaggag
ccatccaatgcctatggactaccagaatcagaatttttaattgttttacgagatgtggtg
ggaggaatgaatcacctccgagagaatggcatagtgcaccgtgacatcaagcccggcaac
atcatgcgcgtcataggggaggacggacagtctgtgtacaagctcacggacttcggggct
gcccgggagctcgaggacgatgagcagttcgtgtcgctctacggcacagaagagtacttg
catccggatatgtatgagagagcagtgctaagaaaagaccatcagaagaagtacggggcc
acagttgacctttggagtatcggagtaacgttttaccacgcagctactgggtcgctgccc
tttagaccatttgaggggcctcgaaggaataaagaagtgatgtataaaataatcactgga
aagccttctggtgcaatatctggagtacagaaagcagaaaatggaccaattgactggagt
gcagacatgcctgtgtcttgtagtctttctcagggtcttcaagcactgcttaccccagtt
cttgcgaacatccttgaagctgatcaggaaaagtgctggggttttgaccagttctttgca
gagactagtgatgtacttcaccgaatgataatccacgttttctcactacagcagatgaca
gcacataagatttacattcatagctacaatactgctgctgtattccatgagctggtctac
aaacaaaccaaaattagttcttcaaatcaagaactcatctatgaaggacgacgcttagtc
ctagaactcggaagactagcccagcatttccccaaaaccacagaggaaaatcctatcttt
gtcataagccgggaacccttacctaccttatctatcttaggattgaaatatgaaaaaatt
tccctacccaaagtacatccacgttatgatttagatggtgatgctagcatggccaaggca
gtgacgggggttgtatgctacgcctgtagaattgccagtacactgctgctctaccaagag
ttaatgcgaaagggggtacgatgggtgattgaattagttaaagatgatttcaatgaaact
gtccacaagaagacagaagtggtgatcacattggagttctgcatcagaaacattgaaaag
actgtgaaagtatatgaaaagttgatgaagatcaacctagaagcagcagagttgggtgaa
atttcagacatacataccaaactgttgagactttccagttctcagggaacaatagaaagc
agtcttcaggacatcaagagcaggttgtctccagggggattgctggctgacacgtgggca
catcaggaaggcacccatccaagagacaggaatgtagaaaaactacaagtcctgttaaat
tgcatcacagagatttactatcagttcaaaaaggacaaagcagaacgcagactagcttat
aatgaagaacagatccacaaatttgataaacaaaaactgtattaccatgcaacaaaagca
atgagccacttcacagatgagtgtgtcagaaagtacgaagtctttctggctaagtcagac
gagtggttgagaaagatgtttcatctcaggaaacagctgtcatcactcactaatcagtgt
tttgatattgaagaggaagtgtccaagtatcaagactacactaatgagttacaggaaact
ctgcctcagaagatgcttgcagcctccagcggactcaagcactccatggcccctgtctac
cccagttctaacaccttagtggagatgactcttggtatgaagaagttgaaggaagagatg
gaaggtgtggttaaggagctggccgagaacaaccacattttggagcggtttgggtcttta
acaatggatggtggcctccgcaatgtggactgtctttag

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