KEGG   Meriones unguiculatus (Mongolian gerbil): 110550916
Entry
110550916         CDS       T05884                                 

Gene name
Stat3
Definition
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
mun  Meriones unguiculatus (Mongolian gerbil)
Pathway
mun01521  EGFR tyrosine kinase inhibitor resistance
mun04062  Chemokine signaling pathway
mun04066  HIF-1 signaling pathway
mun04068  FoxO signaling pathway
mun04217  Necroptosis
mun04550  Signaling pathways regulating pluripotency of stem cells
mun04630  JAK-STAT signaling pathway
mun04659  Th17 cell differentiation
mun04917  Prolactin signaling pathway
mun04920  Adipocytokine signaling pathway
mun04931  Insulin resistance
mun04933  AGE-RAGE signaling pathway in diabetic complications
mun04935  Growth hormone synthesis, secretion and action
mun05145  Toxoplasmosis
mun05160  Hepatitis C
mun05161  Hepatitis B
mun05162  Measles
mun05163  Human cytomegalovirus infection
mun05167  Kaposi sarcoma-associated herpesvirus infection
mun05169  Epstein-Barr virus infection
mun05200  Pathways in cancer
mun05203  Viral carcinogenesis
mun05205  Proteoglycans in cancer
mun05206  MicroRNAs in cancer
mun05212  Pancreatic cancer
mun05221  Acute myeloid leukemia
mun05223  Non-small cell lung cancer
mun05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mun05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:mun00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    110550916 (Stat3)
   04066 HIF-1 signaling pathway
    110550916 (Stat3)
   04068 FoxO signaling pathway
    110550916 (Stat3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    110550916 (Stat3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    110550916 (Stat3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    110550916 (Stat3)
   04062 Chemokine signaling pathway
    110550916 (Stat3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    110550916 (Stat3)
   04917 Prolactin signaling pathway
    110550916 (Stat3)
   04935 Growth hormone synthesis, secretion and action
    110550916 (Stat3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110550916 (Stat3)
   05206 MicroRNAs in cancer
    110550916 (Stat3)
   05205 Proteoglycans in cancer
    110550916 (Stat3)
   05203 Viral carcinogenesis
    110550916 (Stat3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    110550916 (Stat3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    110550916 (Stat3)
   05221 Acute myeloid leukemia
    110550916 (Stat3)
   05223 Non-small cell lung cancer
    110550916 (Stat3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    110550916 (Stat3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    110550916 (Stat3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    110550916 (Stat3)
  09172 Infectious disease: viral
   05162 Measles
    110550916 (Stat3)
   05161 Hepatitis B
    110550916 (Stat3)
   05160 Hepatitis C
    110550916 (Stat3)
   05163 Human cytomegalovirus infection
    110550916 (Stat3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    110550916 (Stat3)
   05169 Epstein-Barr virus infection
    110550916 (Stat3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    110550916 (Stat3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    110550916 (Stat3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mun03000]
    110550916 (Stat3)
Transcription factors [BR:mun03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    110550916 (Stat3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135 DUF4795 Syntaxin-6_N AP1AR Fib_alpha
Other DBs
NCBI-GeneID: 110550916
NCBI-ProteinID: XP_021496879
LinkDB
Position
Unknown
AA seq 770 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMDLTSECATSPM
NT seq 2313 nt   +upstreamnt  +downstreamnt
atggctcagtggaaccagctccagcagctggacacgcggtacctggagcagctccaccag
ctgtacagcgacagcttccccatggagctgcggcagttcctggcaccgtggattgagagt
caagactgggcatacgcagccagcaaagagtcacatgccacattggtgtttcataacctc
ttgggtgagattgaccagcagtacagccgattcctgcaagagtccaacgtcctctaccag
cacaacctgcgaagaatcaagcagttcctgcagagcaggtatcttgagaagccaatggaa
attgcccggatcgtggctcgatgcctgtgggaagagtctcgcctcctccagacagcagcc
acggcggcccagcaagggggccaggccaaccacccaacagctgctgtggtgacagagaag
cagcagatgctggagcagcatcttcaggacgtccggaagcgtgtgcaggatctagaacag
aaaatgaaggtggtggagaatctgcaggacgacttcgacttcaactataaaaccctcaag
agtcaaggagacatgcaggatctgaatggaaacaaccagtccgtgacccgacagaagatg
cagcagctggaacagatgctcacggcgctggaccagatgcggagaagcatcgtgagtgag
ctggcagggcttttgtcagcaatggagtatgtgcagaaaacactcacagacgaagaactg
gccgactggaagaggcgacagcagatcgcgtgcatcggaggccctcccaacatctgcctg
gatcgtctggaaaactggataacgtcgttggcagaatctcaacttcagacccgccagcaa
attaagaagctggaggaactgcagcagaaagtgtcctacaagggggaccctatcgtgcag
caccggccaatgctggaggagaggatcgtggagctgttcagaaacctgatgaaaagcgcc
ttcgtggtggagcggcagccctgcatgccaatgcaccccgaccggcccttggtcatcaag
actggcgtccagttcactaccaaagtcaggttgctggtcaagtttcctgagttgaattat
cagcttaaaattaaagtgtgcattgataaagactctggggacgtcgcggccctcagagga
tctcggaaatttaacattctgggcacgaacacaaaagtgatgaacatggaagagtccaac
aatggcagcctgtctgcagaattcaagcacttgaccctgagggagcagagatgtgggaat
gggggccgtgccaattgtgatgcctccctgatcgtgactgaggagctgcacctgatcacc
ttcgagactgaggtgtaccaccaaggcctcaagatcgacctggagacccactccttgcca
gttgtggtgatctccaacatctgtcagatgccaaatgcttgggcatcgatcctgtggtac
aacatgctgaccaataaccccaagaatgtgaacttcttcaccaagcccccgattggaacc
tgggaccaagtggctgaggtgctcagctggcagttctcgtccaccacgaagcgagggcta
agcatcgagcagctgaccaccctggctgagaagcttctaggacctggtgtgaactactca
gggtgccagattacgtgggctaagttttgcaaagaaaacatggctggcaagggcttctcc
ttctgggtctggctagacaatatcatcgaccttgtgaaaaagtatatcttggccctttgg
aacgaagggtacatcatgggtttcatcagcaaggagcgagagcgggccatcctaagcacg
aagcccccaggcaccttcctgctgcgattcagtgagagcagcaaagaaggaggggtcact
ttcacttgggtggaaaaggacatcagtggcaagacccagatccagtctgtagaaccatac
accaaacagcagctgaacaacatgtcatttgctgaaatcatcatgggctataagatcatg
gatgctaccaacatcctggtgtctccgctggtctacctctatcccgacatccccaaggag
gaggcgttcggaaagtactgccgaccggagagccaggagcaccctgaggctgacccaggt
agtgctgccccctacctgaagaccaagttcatctgtgtgacaccaacgacctgcagcaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataac
ggtgaaggtgctgagccctctgcaggagggcagtttgagtcgctcacatttgacatggat
ctgacctcggagtgcgctacctcccccatgtga

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