KEGG   Meriones unguiculatus (Mongolian gerbil): 110557662
Entry
110557662         CDS       T05884                                 

Gene name
Casp8
Definition
(RefSeq) caspase-8
  KO
K04398  caspase 8 [EC:3.4.22.61]
Organism
mun  Meriones unguiculatus (Mongolian gerbil)
Pathway
mun01524  Platinum drug resistance
mun04115  p53 signaling pathway
mun04210  Apoptosis
mun04215  Apoptosis - multiple species
mun04217  Necroptosis
mun04620  Toll-like receptor signaling pathway
mun04621  NOD-like receptor signaling pathway
mun04622  RIG-I-like receptor signaling pathway
mun04625  C-type lectin receptor signaling pathway
mun04657  IL-17 signaling pathway
mun04668  TNF signaling pathway
mun04932  Non-alcoholic fatty liver disease
mun05010  Alzheimer disease
mun05016  Huntington disease
mun05022  Pathways of neurodegeneration - multiple diseases
mun05132  Salmonella infection
mun05134  Legionellosis
mun05142  Chagas disease
mun05145  Toxoplasmosis
mun05152  Tuberculosis
mun05160  Hepatitis C
mun05161  Hepatitis B
mun05162  Measles
mun05163  Human cytomegalovirus infection
mun05164  Influenza A
mun05165  Human papillomavirus infection
mun05167  Kaposi sarcoma-associated herpesvirus infection
mun05168  Herpes simplex virus 1 infection
mun05169  Epstein-Barr virus infection
mun05170  Human immunodeficiency virus 1 infection
mun05200  Pathways in cancer
mun05203  Viral carcinogenesis
mun05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:mun00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    110557662 (Casp8)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    110557662 (Casp8)
   04215 Apoptosis - multiple species
    110557662 (Casp8)
   04217 Necroptosis
    110557662 (Casp8)
   04115 p53 signaling pathway
    110557662 (Casp8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    110557662 (Casp8)
   04621 NOD-like receptor signaling pathway
    110557662 (Casp8)
   04622 RIG-I-like receptor signaling pathway
    110557662 (Casp8)
   04625 C-type lectin receptor signaling pathway
    110557662 (Casp8)
   04657 IL-17 signaling pathway
    110557662 (Casp8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110557662 (Casp8)
   05203 Viral carcinogenesis
    110557662 (Casp8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    110557662 (Casp8)
   05016 Huntington disease
    110557662 (Casp8)
   05022 Pathways of neurodegeneration - multiple diseases
    110557662 (Casp8)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    110557662 (Casp8)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    110557662 (Casp8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    110557662 (Casp8)
   05134 Legionellosis
    110557662 (Casp8)
   05152 Tuberculosis
    110557662 (Casp8)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    110557662 (Casp8)
   05161 Hepatitis B
    110557662 (Casp8)
   05160 Hepatitis C
    110557662 (Casp8)
   05164 Influenza A
    110557662 (Casp8)
   05162 Measles
    110557662 (Casp8)
   05168 Herpes simplex virus 1 infection
    110557662 (Casp8)
   05163 Human cytomegalovirus infection
    110557662 (Casp8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    110557662 (Casp8)
   05169 Epstein-Barr virus infection
    110557662 (Casp8)
   05165 Human papillomavirus infection
    110557662 (Casp8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    110557662 (Casp8)
   05142 Chagas disease
    110557662 (Casp8)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    110557662 (Casp8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mun01002]
    110557662 (Casp8)
Enzymes [BR:mun01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.61  caspase-8
     110557662 (Casp8)
Peptidases and inhibitors [BR:mun01002]
 Cysteine peptidases
  Family C14: caspase family
   110557662 (Casp8)
SSDB
Motif
Pfam: Peptidase_C14 DED PYRIN
Other DBs
NCBI-GeneID: 110557662
NCBI-ProteinID: XP_021507851
LinkDB
Position
Unknown
AA seq 482 aa
MDFNSCLYEIAENLGSEELAALKFLCLDYIPQKKQESISDALMLFQSLQEKEMLEEGNLS
FLKELLFRIQRLDLLTNVLNSSKEEMVMELQVLDKAQVSPYRVMLFNLSEDVDKLALKSF
KFLLNKEIPKCKLHEDSSLLDIFIEMEKRVILAEGNLNILKSICGQVNKSLLGKIDDYER
SSTERRMSLEGRTESSASLLDGEICLRTLTTWDSPREQDGKAQTSDKAYQMKNKPRGYCL
IFNNNDFSEARKHVPKLRTMKDRKGTNYDEDALTETFKELHFEIMSYKDCRAEEMRQVLR
SYQSMDHKNKDCFVCCILSHGDKGIIYGTDGKEASIYELTSYFTGLKCPSLAGKPKIFFI
QACQGESYQKAVPVETDSQEGDNYLEIDSSSHKNYIPDEADFLLGMATVKNCVSYRDPMH
GTWYIQSLCQSLRERCPQGEDILSILTGVNYDVSNKDDRRNMGKQMPQPTFTLRKKLFFP
PN
NT seq 1449 nt   +upstreamnt  +downstreamnt
atggatttcaacagctgtctttacgaaattgctgaaaacctgggcagtgaagaactggct
gccctcaagtttttgtgcctggactacatcccacagaagaaacaggagtccatcagcgat
gccctgatgctgtttcagagcctgcaggaaaaggaaatgttggaggaaggcaatctgtcc
ttcctgaaggagctgcttttccgaatccaacggctggacctactgaccaacgtcctaaac
agcagcaaggaggagatggtgatggagctgcaggttctagacaaagcccaggtttctccc
tacagggtcatgctctttaatctctcggaagacgtggacaagttggcattgaaatctttt
aagtttcttttgaacaaagagatccccaaatgtaagctgcatgaagactcgagcctgctt
gatattttcatagaaatggagaagagagtcatcctggcggaaggaaacttgaacatcctg
aagtcaatctgtggtcaggtcaacaagagcctgctggggaagatcgacgattatgaaaga
tcaagcacagagagaagaatgagccttgaaggaaggacggagtcgtcagcttcacttctg
gacggggagatatgcttaagaacgctgacaacgtgggactccccaagagaacaagacggc
aaggcccagacatcagacaaggcttaccaaatgaagaacaaacctcggggatactgtctg
atcttcaacaataacgatttcagcgaggcacggaagcatgtacccaagctccgcacaatg
aaggacagaaaaggaacaaactacgatgaagatgctctgactgagacctttaaggagctt
cattttgagataatgtcctacaaggactgcagagcagaggagatgcgccaggtcctgcga
tcctaccaaagcatggaccacaagaacaaagactgctttgtttgctgtatcctctcccac
ggagacaagggcatcatctacggcaccgacgggaaggaagcctccatctatgagctcacg
tcttatttcaccggtttaaagtgtccttccctggctggaaaacccaaaatcttttttatt
caggcttgtcaaggggagagctaccagaaagctgtaccggttgagactgactcacaagag
ggcgacaattatttagaaatagactcatcatctcacaagaactatattccggatgaggcc
gactttctgctggggatggctacggtgaagaactgtgtttcctaccgagatcccatgcat
ggaacctggtacatccagtcactctgccagagcctgagggaaagatgtcctcagggcgaa
gatattctcagcatcctgacaggcgtgaactacgacgtgagcaataaggacgacaggagg
aacatggggaagcagatgcctcagcccaccttcaccctgcgcaagaagctcttcttccct
cctaattga

DBGET integrated database retrieval system