KEGG   Myotis brandtii (Brandt's bat): 102240787Help
Entry
102240787         CDS       T02920                                 

Gene name
DOT1L
Definition
(RefSeq) DOT1 like histone lysine methyltransferase
  KO
K11427  histone-lysine N-methyltransferase, H3 lysine-79 specific [EC:2.1.1.43]
Organism
myb  Myotis brandtii (Brandt's bat)
Pathway
myb00310  Lysine degradation
myb05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:myb00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    102240787 (DOT1L)
 09160 Human Diseases
  09161 Cancers: Overview
   05202 Transcriptional misregulation in cancer
    102240787 (DOT1L)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:myb03036]
    102240787 (DOT1L)
Enzymes [BR:myb01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     102240787 (DOT1L)
Chromosome and associated proteins [BR:myb03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     102240787 (DOT1L)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: DOT1
Motif
Other DBs
NCBI-GeneID: 102240787
NCBI-ProteinID: XP_014389155
LinkDB All DBs
Position
Un
AA seq 1676 aa AA seqDB search
MENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQV
YNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVA
AATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIAN
TSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVV
ELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTT
TPTKVPESKAAVPADTSVDSGAEEEKAATTAIKKPSPSKARKKKLNKKGRKLAGRKRGRP
KKMSTANPERKPKKNPTALDLLHAQTVSQTATPSPQDAYKSPHSPFYQLPPSVQRHPPDQ
LLLAPTPPALQKLLESFKIQYLQFLAYTKTPQYKASLQQLLDQEKEKNARLLGAAQQLFG
HCQAQKEEIKKLFQQKLDELGVKALTYSDLIQAQKEISAHNQQLREQTEQLEKDNRELRS
QSLQLLKARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQ
ELLQLKSCVPPDDAVSLHLRGKGGLGRELEAEPSRLHLELDCSKFSLPHFSSMSPELSMN
GHAASYELCNTLSRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRL
SPAKLVLRRHLSQDHTASGKTPAGELHPRTEHAKENGLPYQSPGLANGIKLSPQDPRPSS
PVALQMTGEKGSEKGLKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPNRA
EKRSTPSPVPQTRESSSTLEKQMGANAHGAGSNAAGSKSLTLAPTGFYAGSVAISGALAG
SPAPLAPGVEPPVFDESSSSGSLFTTMGSRSSTPQHPQLLVQPRNSGPASPTHQLCVSPR
LGAAQGPLPDASKGDLPSEVGFSDPESEAKRRIIFTISAGASSTKQSPSNKHSPLPGGAR
GDSSQSHGQDSRKRGRRKRASAGTPNLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVN
NINQPLEITAISSPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEPGSE
DEQGSTRIERKIATISLESKSPPKTLENGGSLVGRKPMPSSEPINSSKWKSTFSPIADLG
LAKATDSPLQASSALSQNSLFAFRPTLEELSSVDAKLATHPRKSFPGALSGAGGLSPISN
PPNGFAFSGSLAADLSLHSFSDGASLSHKAPEVASLGAPLSFSAPRGKESSTEPGPFVNK
RQLDGLGGPKGEGVKGREGEVSLPVCTPSDKASSHGKVGKGRDREPDFKNGHNLFISAAA
VPPGGLLSGPGLTTAASSASGTAPSSQTHRPFLGTFAPGPQFALGPMSLQANLGSSVLQS
LFSSVPAAAGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGIFNHTVPSASTHPFGASFG
SGAACRSTTLSLTPMQAVASTPASSFQALSSVETRQPPPQPPLPLGRPPAGPPALHAPPP
PPNAALPPAPALLPANSEPVLLQNLAPLPANQAFLPASSAASLPPANASLSIKLASLPHK
VSRPSFMVHHQPLPGLALAQASPMIPQASSTGPSAVWVSLGMPPPYAARLAGVKPR
NT seq 5031 nt NT seq  +upstreamnt  +downstreamnt
atggagaattacgtcctaatcgactacgacaccaaaagcttcgaaagcatgcagaggctc
tgtgataagtacaaccgggccatcgacagcatccaccagctgtggaagggaaccacgcag
cccatgaagctgaatacacggccatccaatgggctcctgcggcacatcctgcagcaggtt
tacaaccactcagtgacggaccctgagaagctcaacaactacgagcccttctccccagag
gtatatggggagacctcctttgacctggtcgcacagatgattgatgagatcaagatgacc
gaggacgacctgtttgtggacctgggaagtggagtgggccaggtcgtgctgcaagtcgcc
gcggccaccaactgcaaacatcactacggagtcgagaaagcggacatcccagccaagtac
gcggagaccatggaccgagagttcaggaagtggatgaaatggtatggaaaaaagcatgca
gaatacacactggaaagaggtgatttcctctcggaggagtggagagagcggatcgccaac
acaagtgttatatttgtgaataactttgcctttggtcctgaggtggatcaccagctgaag
gagcgatttgcaaacatgaaggaaggtggcagaattgtgtcctcgaagccctttgcacct
ctgaacttcagaataaacagtagaaacttgagtgacatcggcaccatcatgcgcgtcgtg
gagctctcgcccctgaagggctcagtgtcgtggacggggaagcccgtctcctactacctg
cacaccatcgaccgcaccatacttgaaaactatttttctagtctgaaaaatccaaaactc
agggaggaacaagaggcagctaggcgccggcagcagcgagaaaacaagagtaatacaacc
acccccacgaaggtgcctgagagcaaggcggctgtgcctgcggacacctctgtggattct
ggtgctgaggaagagaaagcagcgaccaccgctatcaagaagccatccccctccaaagca
cggaagaagaagctgaacaagaagggccggaagctggctggacggaagcgcggacgtccc
aagaagatgagcactgcgaaccctgagcgtaagcccaagaagaaccctactgcactggac
ctcctgcacgcccagactgtgtcccagacggcgacgccctcaccacaagatgcatacaag
tcacctcacagcccattttatcagctacctcccagcgtgcagcggcacccccctgaccag
ctgttgctggcacccaccccgcccgcactgcagaagctgctagagtccttcaagattcag
tacctgcagttcctggcatacacgaagacccctcagtacaaggccagcctgcagcagctg
ctggaccaggagaaggagaagaatgcccgattgctgggtgccgcacagcagctgttcggt
cactgccaggcccagaaagaagaaataaagaagctttttcagcagaaactggatgagttg
ggagtgaaggcgctgacctacagtgacctgatccaagctcagaaagagatctcagctcac
aaccagcagctgcgagagcagacggagcagctggagaaggacaacagggagctgagaagc
cagagcctgcagctgctgaaggctcggtgtgaggagctgaagttggactggtccacactg
tccctggagaacctgctaaaggagaagcaggccctgaagagccagatctccgagaaacag
aggcactgcctggagctgcagatcagcatcgtggagctggaaaagagccagcggcagcag
gagctcctgcaactcaagtcctgcgtgccgcctgatgatgctgtgtccctgcacctacga
gggaaaggtggcctgggccgagaactggaggcggaacccagccggctgcaccttgaactg
gactgctccaaattctccctgccccacttcagtagcatgagcccagagctctccatgaat
ggccacgcggccagctatgagctctgtaacacactgagtcggccctcgtccaagcagaac
accccccagtacctggcctctccactggaccaggaggtggtgccatgtactcccagccac
agcggccggccccggctcgagaagctatctggcttggccttgccagactacaccaggctc
tccccggccaagctggtgctgagacgccacctgagccaggaccacactgccagtggcaag
acacctgctggtgagctacacccacgaactgagcacgccaaggagaatggccttccatac
cagagcccgggcctcgccaatggcatcaagctgagtcctcaggacccacggccctcatcc
cctgtggccttacagatgacaggagaaaaaggcagtgagaagggtctgaaggagcgcgcc
tatgccagcagtggggaggccatcaccagcctacccgtcagcattccactcagcactgtg
cagcccagcaagctgcccgtcagcatccccctggccagcgtggtgttgcccaaccgtgcc
gagaagagaagcacccccagtcctgtgcctcagacccgagagtcctcgtccacacttgaa
aagcagatgggtgctaatgcccatggtgctgggagcaacgctgctgggagcaaaagcctc
accctggcgcccacaggcttctatgcaggctcagtcgccatcagtggggccctggcaggc
agcccggccccactcgctcctggagttgagccccctgtcttcgatgagtcctccagctcg
gggagcctcttcaccaccatgggctcccgcagctccaccccacagcatcctcaactgcta
gtgcaaccccggaactccggtccagcctcgcccacgcaccagctctgcgtcagcccccga
ctcggcgctgcccagggcccactccctgatgcgagcaaaggggaccttccctctgaggtt
ggcttctcagatccagagagcgaggccaagaggaggatcatcttcaccatctcagctggt
gccagcagcaccaagcagtcaccttccaacaagcacagccctctgcctgggggtgctcgt
ggagacagcagtcagagccatgggcaggacagtcgaaagcggggcaggaggaagcgggca
tcagcggggacccccaatctgagctcaggcgtgtcccccaagcgccgggccttgccatct
gtcgccggcctcttcactcagtcttcagggtctcccctcaacctgaactctatggtcaac
aacattaaccaacctttggaaatcacagccatctcgtcccctgagagctccctgaagagc
tcccctgtaccttaccaggacaacgaccagccacccgtgcttaagaaagagaagcccctg
agccagaccaatggagcccactactccccactgacctcagatgaggagccgggctctgag
gacgagcaaggcagcaccagaattgagagaaaaattgcaactatctccttagaaagcaaa
tctcctccgaaaaccttggaaaatggtggcagcctggtaggaaggaagccgatgccctcc
agcgagcccatcaacagcagcaagtggaagtccaccttctcacccatcgctgaccttggc
ctggccaaggctactgacagcccgctacaggccagctccgctctgagccagaactccctg
ttcgcttttcggcccaccctagaggagctcagctcagttgatgccaagctggccacccac
cccaggaagagctttccgggtgcactgtcgggggctggcgggctgagtcccatcagcaac
ccccccaacggctttgccttcagcgggagcctggctgccgacctcagtttacacagtttc
agtgatggtgcttctctctcccacaaggcccctgaggtggccagcctgggcgcccccctg
agcttttccgccccgaggggtaaggagagcagcacggagcctggcccctttgtgaacaag
aggcagctggatggactgggtggcccgaagggtgagggggtcaagggcagggagggagaa
gtcagcttgcccgtgtgcacaccctcagacaaggcctcatcacatggcaaggtgggcaag
ggccgggaccgcgagcctgatttcaaaaatggccacaatctcttcatttctgccgctgcc
gtgcctcctgggggcctcctcagcgggccaggcctcaccacagcagcgtcctcagcaagc
ggcacagccccctcctcccagacacaccggcccttcctgggcacttttgcacctggccca
cagtttgccttgggccccatgtccctgcaggccaacttaggctcatctgtgctgcagtcc
ttgttcagctctgtgccggctgctgctggcctagtgcacgtctcatccgctgcaaccaga
ctgaccaactctcatgccatgggcagcttttcctccggtgtggcaggtggtgcagttgga
ggtatctttaaccacacggtgccttccgcctccactcatccgtttggagccagtttcggc
agcggggctgcttgtcgcagcaccacgctgagcttaaccccgatgcaggcggtggccagt
acccccgcctcttcctttcaggccctgtcctctgtggagaccaggcagcccccaccccag
cctcctctgcccctgggtcggccccctgcggggccaccagcacttcacgcgcccccccct
cctcctaacgctgccttgcctcctgctcctgcactgctccctgctaactctgagcctgtg
ctcctgcagaatcttgcgcccctcccggctaaccaagctttcttacctgcctcctctgcc
gcctctctgcctcctgctaacgcctctctatctatcaagctcgcctccctcccacacaag
gtttcccgcccctccttcatggtgcaccaccagcccctgcctggactggctctggcccag
gcctcacccatgatcccacaggccagctccacggggccatccgccgtgtgggtttccctt
ggcatgccgcctccttatgccgcgcgccttgcgggggttaagccgcgataa

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