Maylandia zebra (zebra mbuna): 101470685
Help
Entry
101470685 CDS
T02814
Gene name
raf1
Definition
(RefSeq) RAF proto-oncogene serine/threonine-protein kinase isoform X1
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
mze
Maylandia zebra (zebra mbuna)
Pathway
mze04010
MAPK signaling pathway
mze04012
ErbB signaling pathway
mze04068
FoxO signaling pathway
mze04140
Autophagy - animal
mze04150
mTOR signaling pathway
mze04210
Apoptosis
mze04218
Cellular senescence
mze04270
Vascular smooth muscle contraction
mze04370
VEGF signaling pathway
mze04371
Apelin signaling pathway
mze04510
Focal adhesion
mze04540
Gap junction
mze04625
C-type lectin receptor signaling pathway
mze04810
Regulation of actin cytoskeleton
mze04910
Insulin signaling pathway
mze04912
GnRH signaling pathway
mze04914
Progesterone-mediated oocyte maturation
mze04916
Melanogenesis
mze05132
Salmonella infection
Brite
KEGG Orthology (KO) [BR:
mze00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101470685 (raf1)
04012 ErbB signaling pathway
101470685 (raf1)
04370 VEGF signaling pathway
101470685 (raf1)
04371 Apelin signaling pathway
101470685 (raf1)
04068 FoxO signaling pathway
101470685 (raf1)
04150 mTOR signaling pathway
101470685 (raf1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101470685 (raf1)
09143 Cell growth and death
04210 Apoptosis
101470685 (raf1)
04218 Cellular senescence
101470685 (raf1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101470685 (raf1)
04540 Gap junction
101470685 (raf1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101470685 (raf1)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
101470685 (raf1)
09152 Endocrine system
04910 Insulin signaling pathway
101470685 (raf1)
04912 GnRH signaling pathway
101470685 (raf1)
04914 Progesterone-mediated oocyte maturation
101470685 (raf1)
04916 Melanogenesis
101470685 (raf1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
101470685 (raf1)
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
101470685 (raf1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mze01001
]
101470685 (raf1)
Enzymes [BR:
mze01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101470685 (raf1)
Protein kinases [BR:
mze01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
101470685 (raf1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
Pkinase_fungal
C1_2
zf-RING_2
zf-C3HC4_2
Motif
Other DBs
NCBI-GeneID:
101470685
NCBI-ProteinID:
XP_004546231
UniProt:
A0A3P9DKF7
LinkDB
All DBs
Position
LG20
AA seq
672 aa
AA seq
DB search
MAHPQGVWKSLSNGFGMKDSPFEGPCLSPTIVQGYPCQRRSSDDSKMPDSKASSTIRVYL
PNQQRTVVNVRPGMTLYHCLIKALRVRGLQPQCCAVFRLNSGQGSRKSRMDWNTDSTSLI
GEELQVEVLDHVPLTTHNFVRKTYLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPT
MCVDWINIRQLLLCQTPGECNAPSVPPPSSRRMRESLTRLPSSAYRYSTPHAFNYAPPTG
GGLSQRQRSTSTPNVHMVSTTLPVDSSVIELDCLNTSPSSWCHRFWLKRKVGIVHFSQSF
VEASPESPEKDAMRDHDSAGSSPNQSPTGWTQSQSKTPAPAQRERAPSLNTQDKIKIRPR
DKRDSSYYWEIEASEVYLHSRIGSGSFGTVFKGKWHGDVAVKILKVTDPTPEQFQAFRNE
VAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHIHVLETNFKMIQLIDIARQTA
QGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKARWSGSHQVEQPSGSILWMA
PEVIRMEDNNPYSFQSDVYSYGIVLFELMTGELPYSQIGNRDQIIFMVGRGYLSPDLSKL
YKNCPKAMKRLVADCTKKSKDERPLFPQILSSIELLQHALPKINRSASEPSLHRATHTED
INACTLTRVPVF
NT seq
2019 nt
NT seq
+upstream
nt +downstream
nt
atggcgcaccctcagggagtgtggaagagcctgagcaacggttttggaatgaaggactct
ccgtttgagggcccctgcctttctccgaccatagtccagggctatccctgccagcgtcgc
tcctcagatgacagcaagatgcccgactcaaaggctagcagcactatccgtgtctacctc
ccgaaccagcaacgcactgtggtaaacgtgcgaccaggtatgactctttaccactgcctg
attaaagcactgagggtgcggggcctgcagcctcagtgctgcgctgtcttcaggctgaat
tcaggacaggggagtagaaaatcacggatggattggaataccgattccacttcactaatt
ggggaagagctgcaggtggaggttttagatcacgtccccttgacaacgcataattttgtt
cgcaaaacatatctgaaactagcgttctgcgatatttgccagaagttccttctgaatggt
ttccgttgccaaacatgtggctacaaattccatgagcattgtagcaccaaagtgcccaca
atgtgtgtggactggatcaatatcaggcaactcttattgtgtcaaacgcccggcgagtgc
aatgccccgtctgtgccaccgccttcgtcccggcgtatgagagagtctttaacgcggctt
ccaagctcagcctaccgttattccacccctcatgccttcaactacgcaccacccactggt
ggcggtctctcccagaggcagcgctccacttctacaccaaatgtccacatggttagcact
actctgcctgtagacagcagcgtgatcgagctagactgcctgaatacctcccccagctcc
tggtgccatagattctggctgaagaggaaagtaggtattgtgcacttctcccagtctttt
gttgaggcctcacctgagagtccagaaaaggatgcaatgcgtgatcatgactcggcgggg
agttcacccaaccagagtcctacaggctggacccaatcccaatccaaaacccctgcacct
gcccagcgagagagggccccatccctcaacactcaggacaaaattaaaataaggcctcgg
gataagcgtgactccagttactactgggagattgaggccagcgaggtttatctgcactcc
cgcattggttccggctccttcggaactgtattcaaaggaaaatggcatggtgatgtagca
gtaaagattttaaaggtgacagaccctacaccagagcagttccaggcattcagaaatgaa
gtggcagtcctcaggaaaacacgacatgtcaacatcctgttgttcatgggttatatgact
aaggacaacctggccattgtgacacagtggtgtgagggtagcagcctctacaagcacata
catgtcctggagacaaatttcaagatgatccagctcatagatattgccaggcagactgct
cagggcatggactatcttcatgcaaagaacatcattcaccgagacatgaaatcaaacaac
attttcttgcatgaagggctaacagtaaaaattggcgactttggtcttgctacggtgaaa
gcaaggtggagtggctcacatcaggtcgagcagccttctggatccattctttggatggct
cctgaggttatccggatggaggataataatccttacagcttccagtctgatgtctattcc
tatggaattgttctctttgagctcatgacgggagagctcccatactcccagataggaaat
agagatcagattatcttcatggtgggaagaggctatctatctccagacctcagcaagctc
tataaaaactgccccaaagccatgaaaaggttggtggctgactgcaccaagaagtccaag
gatgagaggccactctttccacagatcttgtcctccattgagcttctccagcatgccctc
cctaagataaaccgcagtgcctcagaaccgtccctgcacagagccactcacactgaggat
attaatgcctgtactctgaccagagtgcctgttttttag
Maylandia zebra (zebra mbuna): 101471760
Help
Entry
101471760 CDS
T02814
Definition
(RefSeq) serine/threonine-protein kinase A-Raf
KO
K08845
A-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
mze
Maylandia zebra (zebra mbuna)
Pathway
mze04010
MAPK signaling pathway
mze04012
ErbB signaling pathway
mze04068
FoxO signaling pathway
mze04270
Vascular smooth muscle contraction
mze04810
Regulation of actin cytoskeleton
mze04910
Insulin signaling pathway
mze04914
Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:
mze00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101471760
04012 ErbB signaling pathway
101471760
04068 FoxO signaling pathway
101471760
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
101471760
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
101471760
04914 Progesterone-mediated oocyte maturation
101471760
09153 Circulatory system
04270 Vascular smooth muscle contraction
101471760
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mze01001
]
101471760
Enzymes [BR:
mze01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101471760
Protein kinases [BR:
mze01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
101471760
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
Pkinase_fungal
APH
RA
TUG-UBL1
Kdo
C1_2
Motif
Other DBs
NCBI-GeneID:
101471760
NCBI-ProteinID:
XP_004574268
UniProt:
A0A3P9B5E9
LinkDB
All DBs
Position
LG12
AA seq
611 aa
AA seq
DB search
MSSTSSSYSSSGETSPEDPPRGGGTIRVYLPNKQRTVVNVRQGQTVHEILDKALKVRGLS
QECCAVFRLLGGRKRLTDWDTDITPLVGEELLVEVLDDIPLTMHNFVRKTFFKLAYCDFC
HKFLFNGFRCQTCGYKFHQHCSSKVPTVCVDMDTIRERSDPSPCPDGYPQIILPENSPTQ
SNPALTPEPSGMGHLSPSPSSTFHFPMSGGDGQSLQRHRSTSTPNVHMVSTLDPASAMII
EEALKFNNTIGPEPSPKPSTSPPSSFGSPGKKPPKSPSEPRERKPSSSDDKKKVHRGGNR
DSSYYWEVHSREVNIQKRIGSGSFGTVFKGKWHGDVAIKILKVKEPTPEQLQAFKNEMQV
LRKTRHVNILLFMGFMTKPNFAIITQWCEGSSLYRHLHVLESKFDTVRRIDVARQTAQGM
DYLHAKNIIHRDLKSNNIFLHEGWTVKIGDFGLATVKARWTGSQQVEQPSGSILWMAPEV
IRMQDTNPYTFQSDVYGYGVVLFELMSGTLPYSNINNRDQIIFMVGRGYLSPDLSKLYST
SPKAMKRLIVDCLKFKRDERPLFPQILVSIEQVQDLLPKIERSRSEPSLHRAVHAEDLNP
LLFHTTRLMPL
NT seq
1836 nt
NT seq
+upstream
nt +downstream
nt
atgtcctccacctcctcctcctactcctcctcaggggagaccagtccagaggatccaccc
cgaggtggaggaaccatccgagtctacctccccaacaaacagaggacagtggtgaatgtc
cgccaaggacagactgtgcatgagattctagataaagcgctcaaagtgagaggcctgagc
caagagtgctgtgctgtatttcgccttctaggaggtcgaaaaagactgacggactgggac
acagacataactcctctagttggagaggagcttttagttgaggtcctggatgatattccc
ctgaccatgcacaactttgtacgcaaaactttcttcaagctggcttactgtgatttttgc
cacaagttccttttcaatggcttcagatgtcagacatgtggctacaagtttcaccaacac
tgcagtagcaaggtccccaccgtgtgtgtggacatggatactataagagagcgttctgat
cccagtccttgcccagatggatacccacagataatactgccagaaaattcccccacgcag
agcaacccagccttaaccccagagccttctggaatgggccacctgtccccatccccgtcc
tcaacctttcacttccccatgtcaggcggagatggtcagtctctacagaggcatcgctcc
acatctactcccaatgttcatatggtcagcacattggaccctgcttctgccatgattata
gaggaagcactaaagttcaacaacacaataggtcctgaaccctcacctaagccctccacc
agcccgccctcttcttttggctctccagggaagaagccaccaaagtccccttcggaaccc
agggagcgcaagccctcgtcctctgatgacaaaaagaaagtgcaccgaggaggcaacaga
gattcaagttactactgggaggtccactctcgagaagtcaacatccagaagagaataggt
tctggctcctttggaactgtcttcaagggaaagtggcatggagatgtggcaatcaagatc
ctcaaagtcaaagagccaacgcctgagcagttacaagcctttaaaaatgaaatgcaggtg
ttgcggaagacccgccacgtcaacatcctgctgttcatgggcttcatgactaagcccaac
tttgccatcatcacacaatggtgtgaaggcagcagcctgtaccgccatctgcatgtctta
gagagcaagtttgatactgtgcgtcgcattgatgtggccagacagacagcacagggcatg
gattatcttcatgcaaagaacataattcatcgagatctaaaatcaaacaatatttttctc
catgagggctggactgttaaaatcggtgactttggcttggctacagtgaaggctcgatgg
actggctctcagcaggtagaacaacccagcggatccattctctggatggctcctgaggtg
atccgcatgcaggacacaaacccatacacgttccagtcagacgtatatggctacggagta
gttctgtttgagctgatgtcaggaaccctgccttactccaatatcaacaacagagaccag
ataatcttcatggttggacgtggttacctgtctccagacctcagtaagctgtatagtacc
tcacccaaagcaatgaagaggctgatcgtcgactgcctgaagtttaaacgtgatgaaagg
cccctttttccacagattctggtgtccattgagcaggtgcaagatttgctgccgaaaatc
gagcggagtcgctccgagccgtcgctccatcgagctgtccatgctgaggacctgaacccc
ctcctgttccacaccaccaggctcatgcccctctaa
Maylandia zebra (zebra mbuna): 101476445
Help
Entry
101476445 CDS
T02814
Gene name
braf
Definition
(RefSeq) serine/threonine-protein kinase B-raf isoform X1
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
mze
Maylandia zebra (zebra mbuna)
Pathway
mze04010
MAPK signaling pathway
mze04012
ErbB signaling pathway
mze04068
FoxO signaling pathway
mze04150
mTOR signaling pathway
mze04270
Vascular smooth muscle contraction
mze04510
Focal adhesion
mze04810
Regulation of actin cytoskeleton
mze04910
Insulin signaling pathway
mze04914
Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:
mze00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101476445 (braf)
04012 ErbB signaling pathway
101476445 (braf)
04068 FoxO signaling pathway
101476445 (braf)
04150 mTOR signaling pathway
101476445 (braf)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101476445 (braf)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101476445 (braf)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
101476445 (braf)
04914 Progesterone-mediated oocyte maturation
101476445 (braf)
09153 Circulatory system
04270 Vascular smooth muscle contraction
101476445 (braf)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mze01001
]
101476445 (braf)
Enzymes [BR:
mze01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101476445 (braf)
Protein kinases [BR:
mze01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
101476445 (braf)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
C1_2
Pkinase_fungal
APH
Kdo
Motif
Other DBs
NCBI-GeneID:
101476445
NCBI-ProteinID:
XP_004553800
UniProt:
A0A3P9BSY0
LinkDB
All DBs
Position
Unknown
AA seq
822 aa
AA seq
DB search
MAALSSAESPPPVFNGDTTELEPGRERGLDELGAGLDSSCSSGIPGGPQDEEIWNIKQMI
KLTQEHLEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLEAIGNSADFSCSQS
AIPALLEVKIGGCGVGAGPQAFHSAPNTLAVLQTPTDTSRANPRSPQKPIVRVFLPNKQR
TVVPARCGMTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEV
LENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQL
DLLLVSKFFEHHPFTQEEVSSEGTTPVSEACPSLPPSDSTGSICHATVSPSKSIPIPPSF
RPNEEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGLPRSDGAPPTHPACCLRKH
RTRTSSPLLYSYPNDIVFDFEPEPVFRGSTTGLSATPPASLPGSLTNVKVPQKSPCPQRE
RKSSSSSEDRNKMKTLGRRDSSDDWEIPEGQITLGQRIGSGSFGTVFKGKWHGDVAVKML
NVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYTTKPQLAIVTQWCEGSSLYHHLHIIE
TKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWS
GSHQFEQLSGSILWMAPEVIRLQDKNPYSFQSDVYAFGIVLYELMSGALPYSNINNRDQI
IFMVGRGYLSPDLSKVRSNCPKAMKRLMADCLKKKREERPLFPQILASIELLARSLPKIH
RSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGEFSAFK
NT seq
2469 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgttgagcagcgccgagtccccaccgcccgtctttaacggagacactacggag
ctggagccgggcagggagcggggcctggacgagctgggcgccggactggactcgtcctgc
tcgtcggggatcccgggaggtccgcaggatgaggagatctggaacatcaaacagatgata
aagttaacacaagaacatctggaggctctcctggacaagtttggcggagaacacaaccct
ccctccatttatctagaggcctatgaggagtacaccagcaaactggacgctctgcagcag
agggagcagcagctgctggaggccatcgggaacagcgcagacttctcctgctctcagtct
gctataccagcccttctggaagtcaagataggaggttgtggggttggtgcagggcctcag
gctttccactcggccccaaacactttggctgtcctgcagacccccactgacacaagccga
gccaaccctcgctccccccagaaacccattgtcagggtcttcctgcccaacaaacagcga
acagtggtgccggcacgctgtgggatgactgtgagggactccctgaagaaagccttgatg
atgcgaggactcattccagagtgctgtgcagtctataggatacaggatggagagaagaag
cctattggctgggacacagacatctcgtggctgacgggggaggagctgcatgtagaagtg
ttggaaaacgtgccgctcaccacacacaactttgtgaggaagactttctttacactggcc
ttctgtgacttctgcagaaagttgttgttccagggtttccgctgtcagacctgtggctac
aagttccaccagcggtgcagcactgaggttcctctcatgtgcgtcaactacgaccagctc
gacttgctactagtgtccaagttctttgagcaccacccgttcacccaggaggaggtctcc
tcagagggaaccacgcctgtgtctgaggcctgtccatcacttcccccatccgactccact
ggatcaatatgccacgccactgtgtcaccgtccaaatccatacccatcccgcccagtttc
cggcccaacgaggaggaccaccgcaaccagtttggccagcgggaccgttcatcctctgcc
cccaatgtgcacatcaacaccatcgaaccggtcaacatcgatgacctgattcgagatcag
ggcttaccgaggtcagatggagcccccccgacccaccccgcctgctgcttgaggaagcac
cgaacacggacctcaagccccctcctatactcctatcccaatgacatagtgtttgatttt
gagcccgagcccgttttccgaggttcgaccacaggtctgtcggccacacctcccgcctct
ctgcctggctctctgaccaacgtcaaggtcccacagaagtcgccgtgcccgcagagggag
cgcaaatcgtcctcctcgtccgaggaccgcaataagatgaaaaccctggggaggcgggac
tccagtgatgactgggaaatcccggaaggtcagattactctgggtcagaggataggctct
ggatcttttggaactgtcttcaagggaaagtggcacggtgatgtggcagtgaagatgctg
aatgtcaccgctcccacgccacagcagcttcaggcattcaagaatgaagtgggagtcctc
aggaaaacgcgtcacgtgaacatcttgctcttcatgggctacaccaccaagccccagctg
gccatcgtgacccagtggtgtgaaggctccagtctgtaccaccacctgcacatcatcgag
accaagttcgagatgatcaaactgatcgacatagcccgacagaccgctcagggcatggat
tacctgcatgccaagtccatcatacacagagatctgaagagcaacaatattttcctccat
gaggacctaacagtgaagatcggggactttggtctggctacggtgaagtcccgctggagt
ggctcccaccagtttgaacagctttcaggctctattctttggatggctccagaggtaatc
cggctgcaggacaagaacccctacagcttccagtcggacgtgtacgcctttggcatcgta
ctctacgagctgatgtcaggagcgctgccctactccaacatcaacaacagagaccagatc
atattcatggtgggacgaggttacctgtcccctgacctcagcaaggtccgcagcaactgt
ccaaaggccatgaagaggctgatggctgactgcctgaagaagaagagagaggagcggcct
ctcttccctcagattttggcatccattgagctgctggctcgctcgttacccaaaatccac
cgcagcgcctcggagccttcgttaaaccgagctggttttcagacagaggacttcagtttg
tatgcctgcgcctcacctaaaacccccatccaggccggcggttacggggagttttcagca
tttaaataa
DBGET
integrated database retrieval system
