KEGG   NETWORK: N00094Help
Entry
N00094                      Network                                

Name
EGF-Jak-STAT signaling pathway
Definition
EGF -> EGFR -> JAK1 -> STAT1/3/5
  Expanded
1950 -> 1956 -> 3716 -> (6772,6774,6776,6777)
Class
nt06219 JAK-STAT signaling
nt06262 Pancreatic cancer
Type
Reference
Pathway
hsa04630  JAK-STAT signaling pathway
Gene
1950  EGF; epidermal growth factor
1956  EGFR; epidermal growth factor receptor
3716  JAK1; Janus kinase 1
6772  STAT1; signal transducer and activator of transcription 1
6774  STAT3; signal transducer and activator of transcription 3
6776  STAT5A; signal transducer and activator of transcription 5A
6777  STAT5B; signal transducer and activator of transcription 5B
Reference
  Authors
Rane SG, Reddy EP
  Title
Janus kinases: components of multiple signaling pathways.
  Journal
Oncogene 19:5662-79 (2000)
DOI:10.1038/sj.onc.1203925
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