KEGG   NETWORK: N00108Help
Entry
N00108                      Network                                

Name
AML1-ETO fusion to transcriptional activtion
Definition
AML1-ETO => JUP
  Expanded
861v2 => 3728
Class
nt06240 Transcription
nt06275 Acute myeloid leukemia
Type
Variant
Pathway
hsa05221  Acute myeloid leukemia
hsa05202  Transcriptional misregulation in cancer
Disease
H00003  Acute myeloid leukemia
Gene
861  RUNX1; runt related transcription factor 1
3728  JUP; junction plakoglobin
Variant
861v2  AML1-ETO fusion
Reference
  Authors
Muller-Tidow C, Steffen B, Cauvet T, Tickenbrock L, Ji P, Diederichs S, Sargin B, Kohler G, Stelljes M, Puccetti E, Ruthardt M, deVos S, Hiebert SW, Koeffler HP, Berdel WE, Serve H
  Title
Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.
  Journal
Mol Cell Biol 24:2890-904 (2004)
DOI:10.1128/MCB.24.7.2890-2904.2004
Reference
  Authors
Steffen B, Muller-Tidow C, Schwable J, Berdel WE, Serve H.
  Title
The molecular pathogenesis of acute myeloid leukemia.
  Journal
Crit Rev Oncol Hematol 56:195-221 (2005)
DOI:10.1016/j.critrevonc.2004.10.012
LinkDB All DBs

DBGET integrated database retrieval system