KEGG   NETWORK: N00117Help
Entry
N00117                      Network                                

Name
E2A-PBX1 fusion to transcriptional activation
Definition
E2A-PBX1 => WNT16
  Expanded
(6929v1,5087v1) => 51384
Class
nt06240 Transcription
Type
Variant
Pathway
hsa05202  Transcriptional misregulation in cancer
Disease
H00001  B-cell acute lymphoblastic leukemia
Gene
6929  TCF3; transcription factor 3
5087  PBX1; PBX homeobox 1
51384  WNT16; Wnt family member 16
Variant
6929v1  E2A-PBX1 fusion
5087v1  E2A-PBX1 fusion
Reference
  Authors
McWhirter JR, Neuteboom ST, Wancewicz EV, Monia BP, Downing JR, Murre C
  Title
Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia.
  Journal
Proc Natl Acad Sci U S A 96:11464-9 (1999)
DOI:10.1073/pnas.96.20.11464
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