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Entry
N00138                      Network                                

Name
EWSR1-NR4A3
Definition
EWSR-NR4A3 => PPARG
  Expanded
8013v1 => 5468
Class
nt06240 Transcription
Type
Variant
Pathway
hsa05202  Transcriptional misregulation in cancer
Disease
H00053  Extraskeletal myxoid chondrosarcoma
Gene
8013  NR4A3; nuclear receptor subfamily 4 group A member 3
5468  PPARG; peroxisome proliferator activated receptor gamma
Variant
8013v1  EWSR1-NR4A3 fusion
Reference
  Authors
Filion C, Motoi T, Olshen AB, Lae M, Emnett RJ, Gutmann DH, Perry A, Ladanyi M, Labelle Y
  Title
The EWSR1/NR4A3 fusion protein of extraskeletal myxoid chondrosarcoma activates the PPARG nuclear receptor gene.
  Journal
J Pathol 217:83-93 (2009)
DOI:10.1002/path.2445
Reference
  Authors
Nishio J, Iwasaki H, Nabeshima K, Naito M
  Title
Cytogenetics and molecular genetics of myxoid soft-tissue sarcomas.
  Journal
Genet Res Int 2011:497148 (2011)
DOI:10.4061/2011/497148
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