KEGG   NETWORK: N00167Help
Entry
N00167                      Network                                

Name
KSHV vIRF1/3 to p21-cell cycle G1/S
Definition
kshvIRF1/3 -| TP53 => CDKN1A -| CDK4/6 -> RB1 // E2F
  Expanded
(K21653,K21652) -| 7157 => 1026 -| (1019,1021) -> 5925 // (1869,1870,1871)
Class
nt06230 Cell cycle G1/S
nt06130 Cell cycle (virus)
nt06164 Kaposi sarcoma-associated herpesvirus (KSHV)
Type
Virus
Pathway
hsa05167  Kaposi sarcoma-associated herpesvirus infection
Disease
H00041  Kaposi sarcoma
Gene
7157  TP53; tumor protein p53
1026  CDKN1A; cyclin dependent kinase inhibitor 1A
1019  CDK4; cyclin dependent kinase 4
1021  CDK6; cyclin dependent kinase 6
5925  RB1; RB transcriptional corepressor 1
1869  E2F1; E2F transcription factor 1
1870  E2F2; E2F transcription factor 2
1871  E2F3; E2F transcription factor 3
Perturbant
K21653  vIRF1, K9; KSHV interferon regulatory factor-like protein 1
K21652  vIRF3; KSHV interferon regulatory factor-like protein 3
Reference
  Authors
Cai Q, Verma SC, Lu J, Robertson ES
  Title
Molecular biology of Kaposi's sarcoma-associated herpesvirus and related oncogenesis.
  Journal
Adv Virus Res 78:87-142 (2010)
DOI:10.1016/B978-0-12-385032-4.00003-3
LinkDB All DBs

DBGET integrated database retrieval system