KEGG   NETWORK: N00184Help
Entry
N00184                      Network                                

Name
KSHV MIR1/2 to antigen processing and presentation by MHC class I molecules
Definition
kshvMIR1/2 -| MHCI
  Expanded
(K21665,K21666) -| (3105,3106,3107,3133,3134,3135)
Class
nt06229 MHC presentation
nt06129 MHC presentation (virus)
nt06164 Kaposi sarcoma-associated herpesvirus (KSHV)
Type
Virus
Pathway
hsa05167  Kaposi sarcoma-associated herpesvirus infection
Disease
H00041  Kaposi sarcoma
Gene
3105  HLA-A; major histocompatibility complex, class I, A
3106  HLA-B; major histocompatibility complex, class I, B
3107  HLA-C; major histocompatibility complex, class I, C
3133  HLA-E; major histocompatibility complex, class I, E
3134  HLA-F; major histocompatibility complex, class I, F
3135  HLA-G; major histocompatibility complex, class I, G
Perturbant
K21665  MIR1, K3; KSHV E3 ubiquitin-protein ligase MIR1
K21666  MIR2, K5; KSHV E3 ubiquitin-protein ligase MIR2
Reference
  Authors
Ishido S, Wang C, Lee BS, Cohen GB, Jung JU
  Title
Downregulation of major histocompatibility complex class I molecules by Kaposi's sarcoma-associated herpesvirus K3 and K5 proteins.
  Journal
J Virol 74:5300-9 (2000)
DOI:10.1128/JVI.74.11.5300-5309.2000
Reference
  Authors
Liang C, Lee JS, Jung JU
  Title
Immune evasion in Kaposi's sarcoma-associated herpes virus associated oncogenesis.
  Journal
Semin Cancer Biol 18:423-36 (2008)
DOI:10.1016/j.semcancer.2008.09.003
Reference
  Authors
Schulz TF, Cesarman E
  Title
Kaposi Sarcoma-associated Herpesvirus: mechanisms of oncogenesis.
  Journal
Curr Opin Virol 14:116-28 (2015)
DOI:10.1016/j.coviro.2015.08.016
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