| Entry |
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| Name |
KSHV K15 to JNK signaling pathway
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| Definition |
K15 -> MKK4/7 -> JNK -> AP1 |
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| Expanded |
K21651 -> (6416,5609) -> (5599,5601,5602) -> (2353,3725) |
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| Class |
nt06211 Other MAPK signaling
nt06110 MAPK signaling (viruses and bacteria)
nt06164 Kaposi sarcoma-associated herpesvirus (KSHV)
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| Type |
Pathogen
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| Pathway |
| hsa05167 | Kaposi sarcoma-associated herpesvirus infection |
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| Disease |
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| Gene |
| 6416 | MAP2K4; mitogen-activated protein kinase kinase 4 |
| 5609 | MAP2K7; mitogen-activated protein kinase kinase 7 |
| 5599 | MAPK8; mitogen-activated protein kinase 8 |
| 5601 | MAPK9; mitogen-activated protein kinase 9 |
| 5602 | MAPK10; mitogen-activated protein kinase 10 |
| 2353 | FOS; Fos proto-oncogene, AP-1 transcription factor subunit |
| 3725 | JUN; Jun proto-oncogene, AP-1 transcription factor subunit |
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| Perturbant |
| K21651 (K15) | K15; KSHV signal transducing membrane protein |
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| Reference |
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| Authors |
Abere B, Schulz TF |
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| Title |
KSHV non-structural membrane proteins involved in the activation of intracellular signaling pathways and the pathogenesis of Kaposi's sarcoma. |
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| Journal |
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| Reference |
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| Authors |
Schulz TF, Cesarman E |
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| Title |
Kaposi Sarcoma-associated Herpesvirus: mechanisms of oncogenesis. |
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| Journal |
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| Reference |
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| Authors |
Brinkmann MM, Pietrek M, Dittrich-Breiholz O, Kracht M, Schulz TF |
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| Title |
Modulation of host gene expression by the K15 protein of Kaposi's sarcoma-associated herpesvirus. |
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| Journal |
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| Reference |
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| Authors |
Brinkmann MM, Glenn M, Rainbow L, Kieser A, Henke-Gendo C, Schulz TF |
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| Title |
Activation of mitogen-activated protein kinase and NF-kappaB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein. |
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| Journal |
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| LinkDB |
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