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Entry
N00255                      Network                                

Name
Amplified CCNE to cell cycle G1/S
Definition
(CCNE*+CDK2) -> RB1 // E2F
  Expanded
(898v1+1017) -> 5925 // (1869,1870,1871)
Class
nt06230 Cell cycle G1/S
nt06261 Gastric cancer
Type
Variant
Pathway
hsa05226  Gastric cancer
Disease
H00018  Gastric cancer
Gene
898  CCNE1; cyclin E1
1017  CDK2; cyclin dependent kinase 2
5925  RB1; RB transcriptional corepressor 1
1869  E2F1; E2F transcription factor 1
1870  E2F2; E2F transcription factor 2
1871  E2F3; E2F transcription factor 3
Variant
898v1  CCNE amplification
Reference
PMID:7559076
  Authors
Akama Y, Yasui W, Yokozaki H, Kuniyasu H, Kitahara K, Ishikawa T, Tahara E
  Title
Frequent amplification of the cyclin E gene in human gastric carcinomas.
  Journal
Jpn J Cancer Res 86:617-21 (1995)
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