Entry |
|
Name |
Nuclear-initiated estrogen signaling pathway
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Definition |
E2 -- ((ESR1/2)+(NCOA1/2/3)) => (BCL2,EBAG9,KRT19,CTSD,TFF1,PGR) |
Expanded |
C00951 -- ((2099,2100)+(8648,10499,8202)) => (596,9166,3880,1509,7031,5241) |
Class |
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Type |
Reference
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Pathway |
|
Gene |
2099 | ESR1; estrogen receptor 1 |
2100 | ESR2; estrogen receptor 2 |
8648 | NCOA1; nuclear receptor coactivator 1 |
10499 | NCOA2; nuclear receptor coactivator 2 |
8202 | NCOA3; nuclear receptor coactivator 3 |
596 | BCL2; BCL2, apoptosis regulator |
9166 | EBAG9; estrogen receptor binding site associated, antigen, 9 |
7031 | TFF1; trefoil factor 1 |
5241 | PGR; progesterone receptor |
|
Metabolite |
|
Reference |
|
Authors |
Ascenzi P, Bocedi A, Marino M |
Title |
Structure-function relationship of estrogen receptor alpha and beta: impact on human health. |
Journal |
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Reference |
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Authors |
Egeland NG, Lunde S, Jonsdottir K, Lende TH, Cronin-Fenton D, Gilje B, Janssen EA, Soiland H |
Title |
The Role of MicroRNAs as Predictors of Response to Tamoxifen Treatment in Breast Cancer Patients. |
Journal |
|
Reference |
|
Authors |
McDonnell DP, Norris JD |
Title |
Connections and regulation of the human estrogen receptor. |
Journal |
|
Reference |
|
Authors |
Welboren WJ, Sweep FC, Span PN, Stunnenberg HG |
Title |
Genomic actions of estrogen receptor alpha: what are the targets and how are they regulated? |
Journal |
|
Reference |
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Authors |
Carroll JS, Meyer CA, Song J, Li W, Geistlinger TR, Eeckhoute J, Brodsky AS, Keeton EK, Fertuck KC, Hall GF, Wang Q, Bekiranov S, Sementchenko V, Fox EA, Silver PA, Gingeras TR, Liu XS, Brown M |
Title |
Genome-wide analysis of estrogen receptor binding sites. |
Journal |
|
Reference |
|
Authors |
O'Lone R, Frith MC, Karlsson EK, Hansen U |
Title |
Genomic targets of nuclear estrogen receptors. |
Journal |
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LinkDB |
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