KEGG   NETWORK: N00291Help
Entry
N00291                      Network                                

Name
CaSR-PTH signaling pathway
Definition
Ca2+ -> CASR -> GNAQ -> PLCB -> IP3 -> Ca2+ -| PTH
  Expanded
C00076 -> 846 -> 2776 -> (23236,5330,5331,5332) -> C01245 -> C00076 -| 5741
Class
nt06318 CaSR-PTH signaling
Type
Reference
Pathway
hsa04928  Parathyroid hormone synthesis, secretion and action
Gene
846  CASR; calcium sensing receptor
2776  GNAQ; G protein subunit alpha q
23236  PLCB1; phospholipase C beta 1
5330  PLCB2; phospholipase C beta 2
5331  PLCB3; phospholipase C beta 3
5332  PLCB4; phospholipase C beta 4
5741  PTH; parathyroid hormone
Metabolite
C00076  Calcium cation
C01245  D-myo-Inositol 1,4,5-trisphosphate
Reference
  Authors
Bouschet T, Henley JM
  Title
Calcium as an extracellular signalling molecule: perspectives on the Calcium Sensing Receptor in the brain.
  Journal
C R Biol 328:691-700 (2005)
DOI:10.1016/j.crvi.2004.10.006
Reference
  Authors
Khundmiri SJ, Murray RD, Lederer E
  Title
PTH and Vitamin D.
  Journal
Compr Physiol 6:561-601 (2016)
DOI:10.1002/cphy.c140071
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