NETWORK: N00332
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Entry
N00332 Network
Name
Vesicular uptake of lipoproteins
Definition
APOB -> LDLR -- LDLRAP1
Expanded
338 -> 3949 -- 26119
Class
nt06320
APOB-LDLR signaling
Type
Reference
Pathway
hsa04979
Cholesterol metabolism
Gene
338
APOB; apolipoprotein B
3949
LDLR; low density lipoprotein receptor
26119
LDLRAP1; low density lipoprotein receptor adaptor protein 1
Reference
PMID:
22461740
Authors
Go GW, Mani A
Title
Low-density lipoprotein receptor (LDLR) family orchestrates cholesterol homeostasis.
Journal
Yale J Biol Med 85:19-28 (2012)
Reference
PMID:
16129683
Authors
Sirinian MI, Belleudi F, Campagna F, Ceridono M, Garofalo T, Quagliarini F, Verna R, Calandra S, Bertolini S, Sorice M, Torrisi MR, Arca M
Title
Adaptor protein ARH is recruited to the plasma membrane by low density lipoprotein (LDL) binding and modulates endocytosis of the LDL/LDL receptor complex in hepatocytes.
Journal
J Biol Chem 280:38416-23 (2005)
DOI:
10.1074/jbc.M504343200
Reference
PMID:
28299190
Authors
Shapiro MD, Fazio S
Title
Apolipoprotein B-containing lipoproteins and atherosclerotic cardiovascular disease.
Journal
F1000Res 6:134 (2017)
DOI:
10.12688/f1000research.9845.1
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