KEGG   NETWORK: N00336Help
Entry
N00336                      Network                                

Name
PCSK9-mediated LDLR degradation
Definition
PCSK9 -| LDLR
  Expanded
255738 -| 3949
Class
nt06320 APOB-LDLR signaling
Type
Reference
Pathway
hsa04979  Cholesterol metabolism
Gene
255738  PCSK9; proprotein convertase subtilisin/kexin type 9
3949  LDLR; low density lipoprotein receptor
Reference
  Authors
Farnier M
  Title
PCSK9: From discovery to therapeutic applications.
  Journal
Arch Cardiovasc Dis 107:58-66 (2014)
DOI:10.1016/j.acvd.2013.10.007
Reference
  Authors
Costet P, Krempf M, Cariou B
  Title
PCSK9 and LDL cholesterol: unravelling the target to design the bullet.
  Journal
Trends Biochem Sci 33:426-34 (2008)
DOI:10.1016/j.tibs.2008.06.005
LinkDB All DBs

DBGET integrated database retrieval system