KEGG   NETWORK: N00348
Entry
N00348                      Network                                

Name
HPV E6 to p300-p21-Cell cycle G1/S
Definition
E6 -| EP300
  Expanded
K21807 -| 2033
Class
nt06130 Cell cycle (viruses)
nt06166 Human papillomavirus (HPV)
Type
Pathogen
Pathway
hsa05165  Human papillomavirus infection
Disease
H00030  Cervical cancer
Gene
2033  EP300; E1A binding protein p300
Perturbant
K21807 (E6)  E6; HPV protein E6
Reference
  Authors
Moody CA, Laimins LA
  Title
Human papillomavirus oncoproteins: pathways to transformation.
  Journal
Nat Rev Cancer 10:550-60 (2010)
DOI:10.1038/nrc2886
Reference
  Authors
Patel D, Huang SM, Baglia LA, McCance DJ
  Title
The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300.
  Journal
EMBO J 18:5061-72 (1999)
DOI:10.1093/emboj/18.18.5061
Reference
  Authors
Tungteakkhun SS, Duerksen-Hughes PJ
  Title
Cellular binding partners of the human papillomavirus E6 protein.
  Journal
Arch Virol 153:397-408 (2008)
DOI:10.1007/s00705-007-0022-5
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