KEGG   NETWORK: N00455Help
Entry
N00455                      Network                                

Name
CDC25-Cell cycle G2/M
Definition
(ATM,ATR) -> CHEK1/2 -| CDC25B/C -> (CCNB+CDK1)
  Expanded
(472,545) -> (1111,11200) -| (994,995) -> ((891,9133,85417)+983)
Class
nt06130 Cell cycle (viruses)
nt06161 Human immunodeficiency virus type 1 (HIV-1)
Type
Reference
Pathway
hsa04110  Cell cycle
Gene
472  ATM; ATM serine/threonine kinase
545  ATR; ATR serine/threonine kinase
1111  CHEK1; checkpoint kinase 1
11200  CHEK2; checkpoint kinase 2
994  CDC25B; cell division cycle 25B
995  CDC25C; cell division cycle 25C
891  CCNB1; cyclin B1
9133  CCNB2; cyclin B2
85417  CCNB3; cyclin B3
983  CDK1; cyclin dependent kinase 1
Reference
  Authors
Rhind N, Russell P
  Title
Signaling pathways that regulate cell division.
  Journal
Cold Spring Harb Perspect Biol 4:a005942 (2012)
DOI:10.1101/cshperspect.a005942
Reference
  Authors
Shaltiel IA, Krenning L, Bruinsma W, Medema RH
  Title
The same, only different - DNA damage checkpoints and their reversal throughout the cell cycle.
  Journal
J Cell Sci 128:607-20 (2015)
DOI:10.1242/jcs.163766
Reference
  Authors
Biggar KK, Storey KB
  Title
Perspectives in cell cycle regulation: lessons from an anoxic vertebrate.
  Journal
Curr Genomics 10:573-84 (2009)
DOI:10.2174/138920209789503905
Reference
  Authors
Wang Y, Ji P, Liu J, Broaddus RR, Xue F, Zhang W
  Title
Centrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapy.
  Journal
Mol Cancer 8:8 (2009)
DOI:10.1186/1476-4598-8-8
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