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Entry
N00457                      Network                                

Name
HIV Vpr to cell cycle G2M
Definition
hivVpr -| (CCNB+CDK1)
  Expanded
K22202 -| ((891,9133,85417)+983)
Class
nt06130 Cell cycle (viruses)
nt06161 Human immunodeficiency virus type 1 (HIV-1)
Type
Pathogen
Pathway
hsa05170  Human immunodeficiency virus 1 infection
Disease
H01563  HIV infection
Gene
891  CCNB1; cyclin B1
9133  CCNB2; cyclin B2
85417  CCNB3; cyclin B3
983  CDK1; cyclin dependent kinase 1
Perturbant
K22202  vpr; virus protein R
Reference
  Authors
Bagga S, Bouchard MJ
  Title
Cell cycle regulation during viral infection.
  Journal
Methods Mol Biol 1170:165-227 (2014)
DOI:10.1007/978-1-4939-0888-2_10
Reference
PMID:7474080
  Authors
He J, Choe S, Walker R, Di Marzio P, Morgan DO, Landau NR
  Title
Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity.
  Journal
J Virol 69:6705-11 (1995)
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