KEGG   NETWORK: N00462
Entry
N00462                      Network                                

Name
KSHV vCCL1/2/3 to CCR signaling pathway
Definition
(vCCL1,vCCL2,vCCL3) -> (CCR3,CCR4,CCR8)
  Expanded
(K21659,K21657,K21658) -> (1232,1233,1237)
Class
nt06124 Chemokine signaling (viruses)
nt06164 Kaposi sarcoma-associated herpesvirus (KSHV)
Type
Pathogen
Pathway
hsa05167  Kaposi sarcoma-associated herpesvirus infection
Disease
H00041  Kaposi sarcoma
Gene
1232  CCR3; C-C motif chemokine receptor 3
1233  CCR4; C-C motif chemokine receptor 4
1237  CCR8; C-C motif chemokine receptor 8
Perturbant
K21659 (vCCL1)  K6; KSHV protein K6
K21657 (vCCL2)  K4; KSHV macrophage inflammatory protein 2
K21658 (vCCL3)  K4.1; KSHV protein vCCL3
Reference
  Authors
Liang C, Lee JS, Jung JU
  Title
Immune evasion in Kaposi's sarcoma-associated herpes virus associated oncogenesis.
  Journal
Semin Cancer Biol 18:423-36 (2008)
DOI:10.1016/j.semcancer.2008.09.003
Reference
  Authors
Cai Q, Verma SC, Lu J, Robertson ES
  Title
Molecular biology of Kaposi's sarcoma-associated herpesvirus and related oncogenesis.
  Journal
Adv Virus Res 78:87-142 (2010)
DOI:10.1016/B978-0-12-385032-4.00003-3
Reference
  Authors
Schulz TF, Cesarman E
  Title
Kaposi Sarcoma-associated Herpesvirus: mechanisms of oncogenesis.
  Journal
Curr Opin Virol 14:116-28 (2015)
DOI:10.1016/j.coviro.2015.08.016
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