KEGG   NETWORK: N00468
Entry
N00468                      Network                                

Name
EBV BPLF1 to TLR2/4-NFKB signaling pathway
Definition
BPLF1 -| NFKBIA
  Expanded
K22972 -| 4792
Class
nt06121 TLR signaling (viruses and bacteria)
nt06165 Epstein-Barr virus (EBV)
Type
Pathogen
Pathway
hsa05169  Epstein-Barr virus infection
Disease
H00008  Burkitt lymphoma
H00007  Hodgkin lymphoma
H00054  Nasopharyngeal cancer
Gene
4792  NFKBIA; NFKB inhibitor alpha
Perturbant
K22972 (BPLF1)  BPLF1; EBV large tegment protein deneddylase
Reference
  Authors
van Gent M, Braem SG, de Jong A, Delagic N, Peeters JG, Boer IG, Moynagh PN, Kremmer E, Wiertz EJ, Ovaa H, Griffin BD, Ressing ME
  Title
Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling.
  Journal
PLoS Pathog 10:e1003960 (2014)
DOI:10.1371/journal.ppat.1003960
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