KEGG   NETWORK: N00470
Entry
N00470                      Network                                

Name
EBV BGLF4 to RIG-I-like receptor signaling pathway
Definition
BGLF4 -| IRF3
  Expanded
K19455 -| 3661
Class
nt06133 RLR signaling (viruses)
nt06165 Epstein-Barr virus (EBV)
Type
Pathogen
Pathway
hsa05169  Epstein-Barr virus infection
Disease
H00008  Burkitt lymphoma
H00007  Hodgkin lymphoma
H00054  Nasopharyngeal cancer
Gene
3661  IRF3; interferon regulatory factor 3
Perturbant
K19455 (BGLF4)  BGLF4; EBV serine/threonine-protein kinase BGLF4
Reference
  Authors
Hoffmann HH, Schneider WM, Rice CM
  Title
Interferons and viruses: an evolutionary arms race of molecular interactions.
  Journal
Trends Immunol 36:124-38 (2015)
DOI:10.1016/j.it.2015.01.004
Reference
  Authors
Wang JT, Doong SL, Teng SC, Lee CP, Tsai CH, Chen MR
  Title
Epstein-Barr virus BGLF4 kinase suppresses the interferon regulatory factor 3 signaling pathway.
  Journal
J Virol 83:1856-69 (2009)
DOI:10.1128/JVI.01099-08
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