KEGG   NETWORK: N00508
Entry
N00508                      Network                                

Name
HTLV-1 Tax to NFY-mediated transcription
Definition
TAX -> NFYB => MHCII
  Expanded
K21857 -> 4801 => (3108,3109,3111,3112,3113,3115,3117,3118,3119,3122,3123,3125,3126,3127)
Class
nt06160 Human T-cell leukemia virus 1 (HTLV-1)
Type
Pathogen
Pathway
hsa05166  Human T-cell leukemia virus 1 infection
Disease
H00009  Adult T-cell leukemia
Gene
4801  NFYB; nuclear transcription factor Y subunit beta
3108  HLA-DMA; major histocompatibility complex, class II, DM alpha
3109  HLA-DMB; major histocompatibility complex, class II, DM beta
3111  HLA-DOA; major histocompatibility complex, class II, DO alpha
3112  HLA-DOB; major histocompatibility complex, class II, DO beta
3113  HLA-DPA1; major histocompatibility complex, class II, DP alpha 1
3115  HLA-DPB1; major histocompatibility complex, class II, DP beta 1
3117  HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1
3118  HLA-DQA2; major histocompatibility complex, class II, DQ alpha 2
3119  HLA-DQB1; major histocompatibility complex, class II, DQ beta 1
3122  HLA-DRA; major histocompatibility complex, class II, DR alpha
3123  HLA-DRB1; major histocompatibility complex, class II, DR beta 1
3125  HLA-DRB3; major histocompatibility complex, class II, DR beta 3
3126  HLA-DRB4; major histocompatibility complex, class II, DR beta 4
3127  HLA-DRB5; major histocompatibility complex, class II, DR beta 5
Perturbant
K21857 (TAX)  tax; HTLV protein Tax-1
Reference
PMID:9032250
  Authors
Pise-Masison CA, Dittmer J, Clemens KE, Brady JN
  Title
Physical and functional interaction between the human T-cell lymphotropic virus type 1 Tax1 protein and the CCAAT binding protein NF-Y.
  Journal
Mol Cell Biol 17:1236-43 (1997)
DOI:10.1128/MCB.17.3.1236
Reference
  Authors
Boxus M, Twizere JC, Legros S, Dewulf JF, Kettmann R, Willems L
  Title
The HTLV-1 Tax interactome.
  Journal
Retrovirology 5:76 (2008)
DOI:10.1186/1742-4690-5-76
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