KEGG   NETWORK: N00535Help
Entry
N00535                      Network                                

Name
HBV HBx to p53-mediated transcription
Definition
hbvX -| TP53 => (CDKN1A,BAX,FAS)
  Expanded
K21854 -| 7157 => (1026,581,355)
Class
nt06162 Hepatitis B virus (HBV)
Type
Virus
Pathway
hsa05161  Hepatitis B
Disease
H00048  Hepatocellular carcinoma
Gene
7157  TP53; tumor protein p53
1026  CDKN1A; cyclin dependent kinase inhibitor 1A
581  BAX; BCL2 associated X, apoptosis regulator
355  FAS; Fas cell surface death receptor
Perturbant
K21854  X; HBV protein X
Reference
  Authors
Park NH, Song IH, Chung YH
  Title
Chronic hepatitis B in hepatocarcinogenesis.
  Journal
Postgrad Med J 82:507-15 (2006)
DOI:10.1136/pgmj.2006.047431
Reference
PMID:9371515
  Authors
Lin Y, Nomura T, Yamashita T, Dorjsuren D, Tang H, Murakami S
  Title
The transactivation and p53-interacting functions of hepatitis B virus X protein are mutually interfering but distinct.
  Journal
Cancer Res 57:5137-42 (1997)
Reference
  Authors
Lin S, Zhang YJ
  Title
Interference of Apoptosis by Hepatitis B Virus.
  Journal
Viruses 9:E230 (2017)
DOI:10.3390/v9080230
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