KEGG   NETWORK: N00570
Entry
N00570                      Network                                

Name
HSV ICP0 to cGAS-STING signaling pathway
Definition
ICP0 -| TMEM173
  Expanded
K19436 -| 340061
Class
nt06134 CGAS-STING signaling (viruses and bacteria)
nt06168 Herpes simplex virus 1 (HSV-1)
Type
Pathogen
Pathway
hsa05168  Herpes simplex virus 1 infection
Disease
H00365  Herpes simplex virus infection
Gene
340061  TMEM173; transmembrane protein 173
Perturbant
K19436 (ICP0)  ICP0; Simplexvirus E3 ubiquitin-protein ligase ICP0
Reference
  Authors
Zheng C
  Title
Evasion of Cytosolic DNA-Stimulated Innate Immune Responses by Herpes Simplex Virus 1.
  Journal
J Virol 92:e00099-17 (2018)
DOI:10.1128/JVI.00099-17
Reference
  Authors
Su C, Zhan G, Zheng C
  Title
Evasion of host antiviral innate immunity by HSV-1, an update.
  Journal
Virol J 13:38 (2016)
DOI:10.1186/s12985-016-0495-5
Reference
  Authors
Kalamvoki M, Roizman B
  Title
HSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase, and cell derivation.
  Journal
Proc Natl Acad Sci U S A 111:E611-7 (2014)
DOI:10.1073/pnas.1323414111
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