KEGG   NETWORK: N00574Help
Entry
N00574                      Network                                

Name
HSV US11 to oligoadenylate synthetase (OAS)/RNase L pathway
Definition
hsvUS11 -| OAS -> 2-5A -> RNASEL
  Expanded
K19438 -| (4938,4939,4940) -> C20935 -> 6041
Class
nt06137 OAS/RNase L pathway (viruses)
nt06168 Herpes simplex virus 1 (HSV-1)
Type
Pathogen
Pathway
hsa05168  Herpes simplex virus 1 infection
Disease
H00365  Herpes simplex virus infection
Gene
4938  OAS1; 2'-5'-oligoadenylate synthetase 1
4939  OAS2; 2'-5'-oligoadenylate synthetase 2
4940  OAS3; 2'-5'-oligoadenylate synthetase 3
6041  RNASEL; ribonuclease L
Perturbant
K19438  US11; RNA-binding protein
Metabolite
C20935  2-5A
Reference
  Authors
Sanchez R, Mohr I
  Title
Inhibition of cellular 2'-5' oligoadenylate synthetase by the herpes simplex virus type 1 Us11 protein.
  Journal
J Virol 81:3455-64 (2007)
DOI:10.1128/JVI.02520-06
LinkDB All DBs

DBGET integrated database retrieval system