KEGG   NETWORK: N00576
Entry
N00576                      Network                                

Name
HSV UL41/UL13 to IFN signaling pathway
Definition
(UL41,UL13) -> SOCS3 -| JAK1
  Expanded
(K19447,K19440) -> 9021 -| 3716
Class
nt06122 IFN signaling (viruses)
nt06168 Herpes simplex virus 1 (HSV-1)
Type
Pathogen
Pathway
hsa05168  Herpes simplex virus 1 infection
Disease
H00365  Herpes simplex virus infection
Gene
9021  SOCS3; suppressor of cytokine signaling 3
3716  JAK1; Janus kinase 1
Perturbant
K19447 (UL41)  UL41; Simplexvirus virion host shutoff protein
K19440 (UL13)  UL13; Simplexvirus serine/threonine-protein kinase UL13
Reference
  Authors
Yokota S, Yokosawa N, Okabayashi T, Suzutani T, Miura S, Jimbow K, Fujii N
  Title
Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway.
  Journal
J Virol 78:6282-6 (2004)
DOI:10.1128/JVI.78.12.6282-6286.2004
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