KEGG   NETWORK: N00577
Entry
N00577                      Network                                

Name
HSV UL41 to IFN signaling pathway
Definition
UL41 -| JAK1
  Expanded
K19447 -| 3716
Class
nt06122 IFN signaling (viruses)
nt06168 Herpes simplex virus 1 (HSV-1)
Type
Pathogen
Pathway
hsa05168  Herpes simplex virus 1 infection
Disease
H00365  Herpes simplex virus infection
Gene
3716  JAK1; Janus kinase 1
Perturbant
K19447 (UL41)  UL41; Simplexvirus virion host shutoff protein
Reference
  Authors
Chee AV, Roizman B
  Title
Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites.
  Journal
J Virol 78:4185-96 (2004)
DOI:10.1128/JVI.78.8.4185-4196.2004
Reference
  Authors
Fleming SB
  Title
Viral Inhibition of the IFN-Induced JAK/STAT Signalling Pathway: Development of Live Attenuated Vaccines by Mutation of Viral-Encoded IFN-Antagonists.
  Journal
Vaccines (Basel) 4:E23 (2016)
DOI:10.3390/vaccines4030023
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