KEGG   NETWORK: N00580
Entry
N00580                      Network                                

Name
HSV ICP0 to crosstalk between extrinsic and intrinsic apoptotic pathways
Definition
ICP0 -> CASP3
  Expanded
K19436 -> 836
Class
nt06131 Apoptosis (viruses and bacteria)
nt06168 Herpes simplex virus 1 (HSV-1)
Type
Pathogen
Pathway
hsa05168  Herpes simplex virus 1 infection
Disease
H00365  Herpes simplex virus infection
Gene
836  CASP3; caspase 3
Perturbant
K19436 (ICP0)  ICP0; Simplexvirus E3 ubiquitin-protein ligase ICP0
Reference
  Authors
Yu X, He S
  Title
The interplay between human herpes simplex virus infection and the apoptosis and necroptosis cell death pathways.
  Journal
Virol J 13:77 (2016)
DOI:10.1186/s12985-016-0528-0
Reference
  Authors
Sanfilippo CM, Blaho JA
  Title
ICP0 gene expression is a herpes simplex virus type 1 apoptotic trigger.
  Journal
J Virol 80:6810-21 (2006)
DOI:10.1128/JVI.00334-06
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