KEGG   NETWORK: N00689Help
Entry
N00689                      Network                                

Name
MV V/P/C to RIG-I-NFKB signaling pathway
Definition
(mvV,mvP,mvC) -| NFKB => (IFNA,IFNB1)
  Expanded
(K22281,K19377,K22280) -| (4790+5970) => ((3439,3440,3441,3442,3443,3444,3445,3446,3447,3448,3449,3451,3452),3456)
Class
nt06133 RIG-I signaling (viruses)
nt06169 Measles virus (MV)
Type
Pathogen
Pathway
hsa05162  Measles
Disease
H00394  Measles
Gene
4790  NFKB1; nuclear factor kappa B subunit 1
5970  RELA; RELA proto-oncogene, NF-kB subunit
3439  IFNA1; interferon alpha 1
3440  IFNA2; interferon alpha 2
3441  IFNA4; interferon alpha 4
3442  IFNA5; interferon alpha 5
3443  IFNA6; interferon alpha 6
3444  IFNA7; interferon alpha 7
3445  IFNA8; interferon alpha 8
3446  IFNA10; interferon alpha 10
3447  IFNA13; interferon alpha 13
3448  IFNA14; interferon alpha 14
3449  IFNA16; interferon alpha 16
3451  IFNA17; interferon alpha 17
3452  IFNA21; interferon alpha 21
3456  IFNB1; interferon beta 1
Perturbant
K22281  V; measles non-structural protein V
K19377  P; Morbillivirus phosphoprotein
K22280  C; measles protein C
Reference
  Authors
Jiang Y, Qin Y, Chen M
  Title
Host-Pathogen Interactions in Measles Virus Replication and Anti-Viral Immunity.
  Journal
Viruses 8:E308 (2016)
DOI:10.3390/v8110308
Reference
  Authors
Delpeut S, Noyce RS, Siu RW, Richardson CD
  Title
Host factors and measles virus replication.
  Journal
Curr Opin Virol 2:773-83 (2012)
DOI:10.1016/j.coviro.2012.10.008
Reference
  Authors
Schuhmann KM, Pfaller CK, Conzelmann KK
  Title
The measles virus V protein binds to p65 (RelA) to suppress NF-kappaB activity.
  Journal
J Virol 85:3162-71 (2011)
DOI:10.1128/JVI.02342-10
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