KEGG   NETWORK: N00691Help
Entry
N00691                      Network                                

Name
MV V to TLR7/9-IRF7 signaling pathway
Definition
mvV -| IRF7 => IFNA
  Expanded
K22281 -| 3665 => (3439,3440,3441,3442,3443,3444,3445,3446,3447,3448,3449,3451,3452)
Class
nt06121 TLR signaling (viruses and bacteria)
nt06169 Measles virus (MV)
Type
Pathogen
Pathway
hsa05162  Measles
Disease
H00394  Measles
Gene
3665  IRF7; interferon regulatory factor 7
3439  IFNA1; interferon alpha 1
3440  IFNA2; interferon alpha 2
3441  IFNA4; interferon alpha 4
3442  IFNA5; interferon alpha 5
3443  IFNA6; interferon alpha 6
3444  IFNA7; interferon alpha 7
3445  IFNA8; interferon alpha 8
3446  IFNA10; interferon alpha 10
3447  IFNA13; interferon alpha 13
3448  IFNA14; interferon alpha 14
3449  IFNA16; interferon alpha 16
3451  IFNA17; interferon alpha 17
3452  IFNA21; interferon alpha 21
Perturbant
K22281  V; measles non-structural protein V
Reference
  Authors
Jiang Y, Qin Y, Chen M
  Title
Host-Pathogen Interactions in Measles Virus Replication and Anti-Viral Immunity.
  Journal
Viruses 8:E308 (2016)
DOI:10.3390/v8110308
Reference
  Authors
Pfaller CK, Conzelmann KK
  Title
Measles virus V protein is a decoy substrate for IkappaB kinase alpha and prevents Toll-like receptor 7/9-mediated interferon induction.
  Journal
J Virol 82:12365-73 (2008)
DOI:10.1128/JVI.01321-08
LinkDB All DBs

DBGET integrated database retrieval system