KEGG   NETWORK: N00696Help
Entry
N00696                      Network                                

Name
MV C to PKR-eIF2alpha signaling pathway
Definition
mvC -| EIF2AK2 -> EIF2S1
  Expanded
K22280 -| 5610 -> 1965
Class
nt06138 PKR-eIF2alpha signaling (viruses)
nt06169 Measles virus (MV)
Type
Pathogen
Pathway
hsa05162  Measles
Disease
H00394  Measles
Gene
5610  EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2
1965  EIF2S1; eukaryotic translation initiation factor 2 subunit alpha
Perturbant
K22280  C; measles protein C
Reference
  Authors
Toth AM, Devaux P, Cattaneo R, Samuel CE
  Title
Protein kinase PKR mediates the apoptosis induction and growth restriction phenotypes of C protein-deficient measles virus.
  Journal
J Virol 83:961-8 (2009)
DOI:10.1128/JVI.01669-08
Reference
  Authors
Pfaller CK, Radeke MJ, Cattaneo R, Samuel CE
  Title
Measles virus C protein impairs production of defective copyback double-stranded viral RNA and activation of protein kinase R.
  Journal
J Virol 88:456-68 (2014)
DOI:10.1128/JVI.02572-13
Reference
  Authors
Jiang Y, Qin Y, Chen M
  Title
Host-Pathogen Interactions in Measles Virus Replication and Anti-Viral Immunity.
  Journal
Viruses 8:E308 (2016)
DOI:10.3390/v8110308
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