KEGG   NETWORK: N00729
Entry
N00729                      Network                                

Name
IAV NS1 to RIG-I-like receptor signaling pathway
Definition
NS1 -| IRF3
  Expanded
K19396 -| 3661
Class
nt06133 RIG-I signaling (viruses)
nt06170 Influenza A virus (IAV)
Type
Pathogen
Pathway
hsa05164  Influenza A
Disease
H00398  Influenza
Gene
3661  IRF3; interferon regulatory factor 3
Perturbant
K19396 (NS1)  NS1; Influenza A virus non-structural protein 1
Reference
  Authors
van de Sandt CE, Kreijtz JH, Rimmelzwaan GF
  Title
Evasion of influenza A viruses from innate and adaptive immune responses.
  Journal
Viruses 4:1438-76 (2012)
DOI:10.3390/v4091438
Reference
  Authors
Talon J, Horvath CM, Polley R, Basler CF, Muster T, Palese P, Garcia-Sastre A
  Title
Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein.
  Journal
J Virol 74:7989-96 (2000)
DOI:10.1128/JVI.74.17.7989-7996.2000
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