DUOXA2 -> DUOX2 -> H2O2

405753 -> 50506 -> C00027

nt06322 TRH-TSH-TH signaling

Reference

PMID:16651268

Grasberger H, Refetoff S

Identification of the maturation factor for dual oxidase. Evolution of an eukaryotic operon equivalent.

J Biol Chem 281:18269-72 (2006)
DOI:10.1074/jbc.C600095200

PMID:24492313

MacFie TS, Poulsom R, Parker A, Warnes G, Boitsova T, Nijhuis A, Suraweera N, Poehlmann A, Szary J, Feakins R, Jeffery R, Harper RW, Jubb AM, Lindsay JO, Silver A

DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid.

Inflamm Bowel Dis 20:514-24 (2014)
DOI:10.1097/01.MIB.0000442012.45038.0e

PMID:31083324

Szanto I, Pusztaszeri M, Mavromati M

H2O2 Metabolism in Normal Thyroid Cells and in Thyroid Tumorigenesis: Focus on NADPH Oxidases.

Antioxidants (Basel) 8:E126 (2019)
DOI:10.3390/antiox8050126