KEGG   NETWORK: N00805
Entry
N00805                      Network                                

Name
Bile acid biosynthesis
Definition
Cholesterol -- (CYP7A1,CYP7B1,CYP39A1) >> HSD3B7 >> CYP8B1 >> AKR1D1 >> AKR1C4 >> CYP27A1 >> SLC27A5 >> AMACR >> ACOX2 >> HSD17B4 >> SCP2 >> ACOT8 -> Cholate
  Expanded
C00187 -- (1581,9420,51302) >> 80270 >> 1582 >> 6718 >> 1109 >> 1593 >> 10998 >> 23600 >> 8309 >> 3295 >> 6342 >> 10005 -> C00695
Class
nt06022 Bile acid biosynthesis
Type
Reference
Pathway
hsa00120  Primary bile acid biosynthesis
Gene
1581  CYP7A1; cytochrome P450 family 7 subfamily A member 1
9420  CYP7B1; cytochrome P450 family 7 subfamily B member 1
51302  CYP39A1; cytochrome P450 family 39 subfamily A member 1
80270  HSD3B7; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
1582  CYP8B1; cytochrome P450 family 8 subfamily B member 1
6718  AKR1D1; aldo-keto reductase family 1 member D1
1109  AKR1C4; aldo-keto reductase family 1 member C4
1593  CYP27A1; cytochrome P450 family 27 subfamily A member 1
10998  SLC27A5; solute carrier family 27 member 5
23600  AMACR; alpha-methylacyl-CoA racemase
8309  ACOX2; acyl-CoA oxidase 2
3295  HSD17B4; hydroxysteroid 17-beta dehydrogenase 4
6342  SCP2; sterol carrier protein 2
10005  ACOT8; acyl-CoA thioesterase 8
Metabolite
C00187  Cholesterol
C00695  Cholic acid
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