KEGG   NETWORK: N00868
Entry
N00868                      Network                                

Name
Pyrin Inflammasome signaling pathway
Definition
(MEFV+PYCARD) -> CASP1 -> (IL1B,IL18)
  Expanded
(4210+29108) -> 834 -> (3553,3606)
Class
nt06139 NLR signaling (viruses and bacteria)
Type
Reference
Pathway
hsa04621 NOD-like receptor signaling pathway   
Gene
4210  MEFV; MEFV innate immuity regulator, pyrin
29108  PYCARD; PYD and CARD domain containing
834  CASP1; caspase 1
3553  IL1B; interleukin 1 beta
3606  IL18; interleukin 18
Reference
  Authors
Heilig R, Broz P
  Title
Function and mechanism of the pyrin inflammasome.
  Journal
Eur J Immunol 48:230-238 (2018)
DOI:10.1002/eji.201746947
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