KEGG   NETWORK: N00943
Entry
N00943                      Network                                

Name
Shigella IpaH4.5 to TNF-NFKB signaling pathway
Definition
IpaH4.5 -| RELA
  Expanded
K23830 -| 5970
Class
nt06123 TNF signaling (viruses and bacteria)
Type
Pathogen
Pathway
hsa05131  Shigellosis
Disease
H00299  Shigellosis
Gene
5970  RELA; RELA proto-oncogene, NF-kB subunit
Perturbant
K23830 (IpaH4.5)  ipaH4.5; E3 ubiquitin-protein ligase IpaH4.5
Reference
  Authors
Wang F, Jiang Z, Li Y, He X, Zhao J, Yang X, Zhu L, Yin Z, Li X, Wang X, Liu W, Shang W, Yang Z, Wang S, Zhen Q, Zhang Z, Yu Y, Zhong H, Ye Q, Huang L, Yuan J
  Title
Shigella flexneri T3SS effector IpaH4.5 modulates the host inflammatory response via interaction with NF-kappaB p65 protein.
  Journal
Cell Microbiol 15:474-85 (2013)
DOI:10.1111/cmi.12052
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