KEGG   NETWORK: N00945
Entry
N00945                      Network                                

Name
Shigella IpaH1.4/2.5 to TNF-NFKB signaling pathway
Definition
IpaH1.4/2.5 -| RFN31 -> RIPK1
  Expanded
K23828 -| 55072 -> 8737
Class
nt06123 TNF signaling (viruses and bacteria)
Type
Pathogen
Pathway
hsa05131  Shigellosis
Disease
H00299  Shigellosis
Gene
55072  RNF31; ring finger protein 31
8737  RIPK1; receptor interacting serine/threonine kinase 1
Perturbant
K23828 (IpaH1.4/2.5)  ipaH1.4_2.5; E3 ubiquitin-protein ligase IpaH1.4/2.5
Reference
  Authors
de Jong MF, Liu Z, Chen D, Alto NM
  Title
Shigella flexneri suppresses NF-kappaB activation by inhibiting linear ubiquitin chain ligation.
  Journal
Nat Microbiol 1:16084 (2016)
DOI:10.1038/nmicrobiol.2016.84
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