KEGG   NETWORK: N00952
Entry
N00952                      Network                                

Name
Shigella IpgB1 to ITGA/B-RHOG-RAC signaling pathway
Definition
IpgB1 -> (DOCK1+ELMO) -> RAC1
  Expanded
K13742 -> (1793+(9844,63916,79767)) -> 5879
Class
nt06135 Cytoskeletal regulation (viruses and bacteria)
Type
Pathogen
Pathway
hsa05131  Shigellosis
Disease
H00299  Shigellosis
Gene
1793  DOCK1; dedicator of cytokinesis 1
9844  ELMO1; engulfment and cell motility 1
63916  ELMO2; engulfment and cell motility 2
79767  ELMO3; engulfment and cell motility 3
5879  RAC1; Rac family small GTPase 1
Perturbant
K13742 (IpgB1)  ipgB1; protein IpgB1
Reference
  Authors
Handa Y, Suzuki M, Ohya K, Iwai H, Ishijima N, Koleske AJ, Fukui Y, Sasakawa C
  Title
Shigella IpgB1 promotes bacterial entry through the ELMO-Dock180 machinery.
  Journal
Nat Cell Biol 9:121-8 (2007)
DOI:10.1038/ncb1526
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