KEGG   NETWORK: N01094
Entry
N01094                      Network                                

Name
Escherichia Eae/Tir/TccP to Actin signaling pathway
Definition
Eae -> Tir -> (IRTKS,IRSp53) -> TccP -> WASL -> ARP2/3 -> (ACTB,ACTG1)
  Expanded
K12790 -> K12784 -> (55971,10458) -> K12789 -> 8976 -> (10097+10096+10552+10095+10109+10094+10093+10092+81873) -> (60,71)
Class
nt06135 Cytoskeletal regulation (viruses and bacteria)
Type
Pathogen
Pathway
hsa05130  Pathogenic Escherichia coli infection
Disease
H00277  Enterohemorrhagic Escherichia coli (EHEC) infection
H00278  Enteropathogenic Escherichia coli (EPEC) infection
Gene
55971  BAIAP2L1; BAR/IMD domain containing adaptor protein 2 like 1
10458  BAIAP2; BAR/IMD domain containing adaptor protein 2
8976  WASL; WASP like actin nucleation promoting factor
10097  ACTR2; actin related protein 2
10096  ACTR3; actin related protein 3
10552  ARPC1A; actin related protein 2/3 complex subunit 1A
10095  ARPC1B; actin related protein 2/3 complex subunit 1B
10109  ARPC2; actin related protein 2/3 complex subunit 2
10094  ARPC3; actin related protein 2/3 complex subunit 3
10093  ARPC4; actin related protein 2/3 complex subunit 4
10092  ARPC5; actin related protein 2/3 complex subunit 5
81873  ARPC5L; actin related protein 2/3 complex subunit 5 like
60  ACTB; actin beta
71  ACTG1; actin gamma 1
Perturbant
K12790 (Eae)  eae; intimin
K12784 (Tir)  tir; translocated intimin receptor
K12789 (TccP)  tccP; Tir-cytoskeleton coupling protein
Reference
  Authors
Lai Y, Rosenshine I, Leong JM, Frankel G
  Title
Intimate host attachment: enteropathogenic and enterohaemorrhagic Escherichia coli.
  Journal
Cell Microbiol 15:1796-808 (2013)
DOI:10.1111/cmi.12179
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