KEGG   NETWORK: N01113
Entry
N01113                      Network                                

Name
Salmonella SseK1 to TNF-NFKB signaling pathway
Definition
SseK1 -| (RIPK1+TRADD+TRAF2/5)
  Expanded
K23944 -| (8737+8717+(7186,7188))
Class
nt06123 TNF signaling (viruses and bacteria)
Type
Pathogen
Pathway
hsa05132  Salmonella infection
Disease
H00113  Salmonellosis
Gene
8737  RIPK1; receptor interacting serine/threonine kinase 1
8717  TRADD; TNFRSF1A associated via death domain
7186  TRAF2; TNF receptor associated factor 2
7188  TRAF5; TNF receptor associated factor 5
Perturbant
K23944 (SseK1)  sseK1; type III secretion system effector arginine glycosyltransferase
Reference
  Authors
El Qaidi S, Chen K, Halim A, Siukstaite L, Rueter C, Hurtado-Guerrero R, Clausen H, Hardwidge PR
  Title
NleB/SseK effectors from Citrobacter rodentium, Escherichia coli, and Salmonella enterica display distinct differences in host substrate specificity.
  Journal
J Biol Chem 292:11423-11430 (2017)
DOI:10.1074/jbc.M117.790675
Reference
  Authors
Newson JPM, Scott NE, Yeuk Wah Chung I, Wong Fok Lung T, Giogha C, Gan J, Wang N, Strugnell RA, Brown NF, Cygler M, Pearson JS, Hartland EL
  Title
Salmonella Effectors SseK1 and SseK3 Target Death Domain Proteins in the TNF and TRAIL Signaling Pathways.
  Journal
Mol Cell Proteomics 18:1138-1156 (2019)
DOI:10.1074/mcp.RA118.001093
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