KEGG   NETWORK: N01117
Entry
N01117                      Network                                

Name
Salmonella GogB to TNF-NFKB signaling pathway
Definition
GogB -| SKP1 -> NFKBIA
  Expanded
K23942 -| 6500 -> 4792
Class
nt06123 TNF signaling (viruses and bacteria)
Type
Pathogen
Pathway
hsa05132  Salmonella infection
Disease
H00113  Salmonellosis
Gene
6500  SKP1; S-phase kinase associated protein 1
4792  NFKBIA; NFKB inhibitor alpha
Perturbant
K23942 (GogB)  gogB; Gifsy-1 prophage leucine-rich repeat protein
Reference
  Authors
Pilar AV, Reid-Yu SA, Cooper CA, Mulder DT, Coombes BK
  Title
GogB is an anti-inflammatory effector that limits tissue damage during Salmonella infection through interaction with human FBXO22 and Skp1.
  Journal
PLoS Pathog 8:e1002773 (2012)
DOI:10.1371/journal.ppat.1002773
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