KEGG   NETWORK: N01118
Entry
N01118                      Network                                

Name
Salmonella SpvD to TNF-NFKB signaling pathway
Definition
SpvD -| XPO2 -> (KPNA1+KPNA3) -> NFKB
  Expanded
K19557 -| 1434 -> (3836+3839) -> (4790+5970)
Class
nt06123 TNF signaling (viruses and bacteria)
Type
Pathogen
Pathway
hsa05132  Salmonella infection
Disease
H00113  Salmonellosis
Gene
1434  CSE1L; chromosome segregation 1 like
3836  KPNA1; karyopherin subunit alpha 1
3839  KPNA3; karyopherin subunit alpha 3
4790  NFKB1; nuclear factor kappa B subunit 1
5970  RELA; RELA proto-oncogene, NF-kB subunit
Perturbant
K19557 (SpvD)  spvD; salmonella plasmid virulence protein D
Reference
  Authors
Rolhion N, Furniss RC, Grabe G, Ryan A, Liu M, Matthews SA, Holden DW
  Title
Inhibition of Nuclear Transport of NF-kB p65 by the Salmonella Type III Secretion System Effector SpvD.
  Journal
PLoS Pathog 12:e1005653 (2016)
DOI:10.1371/journal.ppat.1005653
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